Propoxyphene

Usual Dosing (Adults)

HCL salt: 65 mg q3-4 hours prn pain (maximum: 390 mg/day).

Napsylate salt: 100 mg q4h prn pain (maximum: 600 mg/day).

Renal Dosing

[> 10 ml/min]: No change.

[<10]: Avoid. (Serum concentrations of propoxyphene may be increased to toxic levels.)

Hemodialysis

Avoid.

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
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