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Usual Dosing (Adults)

200-400 mg po or IV q12h.

Renal Dosing

dialysis [> 50 ml/min]: no changes

[20-50]: 200-400mg q24h.

[<20]: 100-200mg q24h (one-half of usual dose q24h.)


dialysis Hemodialysis:  Manufacturer states: For CRCL <20 ml/min give 50% of usual dose q24h. No specific info for hemodialysis. 

Continuous arteriovenous or venovenous hemodiafiltration effects: Administer 300 mg every 24 hours


National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
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