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Usual Dosing (Adults)

Herpes Zoster: 500mg po q8h x 7 days.
Recurrent herpes simplex (genital): 125 mg po bid x 5 days.
Primary Genital herpes simplex: 250 mg po tid x 5-10 days.
Genital-chronic suppression: 250 mg po bid.

Renal Dosing

dialysis [>60 ml/min] No change

[40-59] Zoster: 500mg q12h. No changes to other regimens.

[20-39]: Zoster: 500mg q24h. Recurrent GH: 125mg q24h. GH suppression: 125mg q12h. 

[<20]: Zoster: 250mg q24h. Recurrent GH: 125mg q24h. GH suppression: 125mg q24h. 


dialysis Recurrent Genital herpes or suppression: 125mg after each dialysis.
Zoster or genitial herpes in HIV pt: 250mg after each dialysis.


National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.


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