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Usual Dosing (Adults)

IV: 750 mg to 1.5 gm IV q8h.
Oral: 250 – 500mg q12h. 

Renal Dosing

dialysis Oral:
[CRCL >10 ml/min]: no changes

[<10 ml/min]: give 250mg q24h. 

[CRCL >20 ml/min]: no changes
(750 mg to 1.5 gm IV q8h)

[10-20 ]: 750 mg q12h. 

[<10 ml/min]: 750 mg q24h.


dialysis IV:  Hemodialysis:  750mg q24h. Repeat the dose at the end of dialysis. PD: 750 mg q24h.

Oral:  Give 250 mg q24h. Repeat the dose after dialysis.


National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.