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Usual Dosing (Adults)

1-2g per day divided qd or q12h

Renal Dosing

dialysis PO:
[CRCL >50 ]: No change. 
[10-25 m/min]: Administer every 24 hours.
[<10 ml/min]: Administer every 36 hours.
[25-50 ]: 1 gram x 1, then 500mg q12h. 
[10-25 ]: 1 gram po x 1, then 500mg q24h. 
[<10 ]: 1 gram x 1, then 500 mg q36h.


dialysis 0.5-1g after each dialysis.  
Alternatives:  1 gram x 1, then 500 mg q36h. Dose should be given after dialysis on dialysis days  (OR) give 1 gram after each hemodialysis session plus an additional 1 gram dose q72h.


National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
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