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Usual Dosing (Adults)

250 to 500 mg po q8h or if the extended release form is used: 375–500 mg q12h.

Renal Dosing

dialysis PO:
[CRCL >50 ]: no change. 
[10 - 50]: Administer 50% to 100% of dose at same interval.
[<10 ]: Give 50% of usual dose at same interval.


dialysis 250mg 12 hours. Make sure dose is given after dialysis.
Moderately dialyzable (20% to 50%)


National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.


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