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MedlinePlus is a service of the National Library of Medicine (NLM), the world's largest medical library, which is part of the National Institutes of Health (NIH). It was built as an online health information resource for patients and their families and friends.

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Tetanus, Diphtheria, and Pertussis Vaccines

Tetanus, diphtheria, and pertussis (whooping cough) are serious bacterial infections:

  • Tetanus is an uncommon disease that requires immediate treatment in a hospital. It causes painful tightening of the muscles, usually all over the body. It can lead to "locking" of the jaw.
  • Diphtheria usually affects the nose and throat. But it can also affect the skin and other body parts.
  • Whooping cough can cause uncontrollable coughing fits. It may begin like a cold, but unlike a cold, the coughing can last for weeks or months.

Vaccines can protect you from these diseases. In the U.S., there are three combination vaccines:

  • DTaP (diphtheria, tetanus, and pertussis) prevents all three diseases. It is for babies and children under age 7. There are several different DTaP vaccines. Some of them also protect against other diseases.
  • Tdap (tetanus, diphtheria, and pertussis) also prevents all three diseases. It is for older children and adults.
  • Td (tetanus and diphtheria) prevents those two diseases. It is for older children and adults. It is usually given as a booster dose every 10 years. You may also get it after 5 years if you get a severe or dirty wound or burn.

Some people should not get these vaccines, including those who have had severe reactions to the shots before. Check with your health care provider first if you have seizures, a neurologic problem, or Guillain-Barre syndrome.

People with minor illnesses such as a cold can get vaccinated. But those who are more ill may need wait until they feel better before getting some vaccines.

Centers for Disease Control and Prevention




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