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MedlinePlus is a service of the National Library of Medicine (NLM), the world's largest medical library, which is part of the National Institutes of Health (NIH). It was built as an online health information resource for patients and their families and friends.

MedlinePlus presents high-quality, easy to understand, relevant health and wellness information that is trusted.

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MedlinePlus at a Glance

  • Offers information on health topics, human genetics, medical tests, medications, dietary supplements, and healthy recipes.
  • Sourced from more than 1,600 selected organizations.
  • Provides 40,000 links to authoritative health information in English and 18,000 links to information in Spanish.
  • In 2018, 277 million users viewed MedlinePlus more than 700 million times.

Granulomatosis with Polyangiitis

Granulomatosis with polyangiitis (GPA), previously known as Wegener's granulomatosis, is a rare disease. It is a type of vasculitis, or inflammation of the blood vessels. The inflammation limits the flow of blood to important organs, causing damage. It can affect any organ, but it mainly affects the sinuses, nose, trachea (windpipe), lungs, and kidneys.

The cause of GPA is unknown. It can affect people at any age. Men and women are equally affected. It is more common in whites. Symptoms may include joint pain, weakness, tiredness, and cold symptoms such as a runny nose that doesn't get better. Doctors use blood tests, chest X-rays, and biopsies to diagnose GPA and rule out other causes of the symptoms.

Early treatment is important. Most people improve with medicines to slow or stop the inflammation.




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