Archives: Medical

General principles involved in the extemporaneous compounding of ophthalmic preparations This document Copyright © 2002 D.McAuley, GlobalRPh Inc. All Rights Reserved.                 There are several important factors to consider when called upon to compound a sterile ophthalmic preparation .         In many

Alteplase - Clearing Catheter Occlusions Intracatheter:   Cathflo® Activase® (Alteplase) is for instillation into the dysfunctional catheter at a concentration of 1 mg/mL. DOSAGE AND ADMINISTRATION • Patients weighing >/=30 kg: 2 mg in 2 mL. • Patients weighing <30 kg: 110% of the internal lumen volume of the

Common Drug levels Drug Usual therapeutic range Amikacin Peak: 25-35   trough: 4-8 mcg/ml aminophylline 10 to 20 mcg/ml carbamazepine 4 to 12 mcg/ml amitriptyline 120 to 150 ng/ml desipramine 150 to 300 ng/ml  digoxin 0.8 to 2.0 ng/ml   (Steady state: 7- 10 days) disopyramide 2 to 5 mcg/ml  ethosuximide 40 to 100 mcg/mL Gentamicin Conventional dosing: Peak: 4-10 mcg/ml. Trough:  0.5 to 2 mcg/ml lidocaine 1.5 to

Nine Essential amino acids Essential amino acids cannot be synthesized by the body and therefore it is 'essential' to include them in  the diet. histidine,  leucine,  isoleucine,  lysine, methionine, phenylalanine, threonine,  tryptophan,  valine. Estimated daily requirements for an adult based on the World Health Organization (WHO) guidelines: Amino acid mg/kilogram 70 kg adult Histidine 10 700

How does pregabalin compare to gabapentin in the treatment of neuropathic pain? David F. McAuley, Pharm.D. GlobalRPh Inc. Pregabalin versus gabapentin: Pregabalin, like gabapentin, is an amino acid derivative of gamma-amino butyric acid (GABA analogue).1,2 Pregabalin is the pharmacologically active S-enantiomer of 3-aminomethyl-5-methyl-hexanoic acid, and has a similar pharmacological profile to gabapentin.1 These agents

David F. McAuley, Pharm.D. GlobalRPh Inc. Introduction:  Closridium difficile is the primary cause of nosocomial gastrointestinal illness in adult patients.1,2,3  Also, the most common site of infection with this organism is the colon.1 The universal recommendation in adult patients diagnosed with C.difficile colitis is to discontinue, whenever possible, the antibiotic that

Cerebrospinal fluid (CSF) analysis - Meningitis Normal values (CSF): CSF opening pressure: 50–180 mmH2O Glucose: 40–85 mg/dL. Protein (total): 15–45 mg/dL. Lactate dehyrogenase: 1/10 of serum level. Lactate: less than 35 mg/dL. Leukocytes (WBC): 0–5/µL (adults / children); up to 30/µL (newborns). Gram stain: negative. Culture: sterile. Specific gravity: 1.006–1.009. Syphilis serology: negative. Gross appearance: Normal CSF is clear and colorless. Differential: 60–70%

Question: Please define the Anion Gap and its utility in diagnosis and how it relates to osmolality. Anion Gap The anion gap provides an estimation of the unmeasured anions in the plasma and is useful in the setting of arterial blood gas analysis. It is especially useful in helping to differentiate the

Using this table: To convert from a conventional unit to a SI Unit, multiply  by the conversion factor listed (eg Albumin  3 g/dl  x 10 = 30 g/L.   To convert from SI Units to conventional units, divide by the listed conversion factor. This document Copyright © 2003-2012 D.McAuley, GlobalRPh Inc.

David F. McAuley, Pharm D. Introduction: The initial interventions used to treat shock are aimed at reversing the underlying cause if possible and the administration of intravenous fluids.1,2,3 If these interventions are not successful, catecholamines such as dopamine, epinephrine and/or norepinephrine are administered in order to help support systemic circulation.2,3 However,