Archives: Medical

Understanding Dietary Fiber: Types, Benefits, and Requirements Dietary fiber, a crucial component of a balanced diet, has garnered significant attention from Healthcare professionals due to its myriad health benefits. This complex carbohydrate, which passes through the digestive system largely undigested, plays a vital role in maintaining optimal health and

David F. McAuley, Pharm.D. GlobalRPh Inc. Introduction: Pulmonary arterial hypertension (PAH) is a progressive, and often fatal, debilitating disorder.1,2  The clinical hallmarks of this disease include: 1) progressive breathlessness 2) exertion limitation and 3) frequent decline and failure of the right ventricle.2  It is estimated that pulmonary arterial hypertension (PAH) affects 100,000 patients

David F. McAuley, Pharm D. GlobalRPh Inc. Introduction:  Nephropathy is one of the most common microvascular complications associated with diabetes and it is currently the leading cause of end-stage renal disease.1,2,3  Diabetic nephropathy accounts for roughly 40% of all new cases seen in the United States each year.1,2  One of the

David F. McAuley, Pharm.D.GlobalRPh Inc. Introduction: Generalized pruritus is a common, and often distressing, complication of cholestasis and certain non-cholestatic chronic liver diseases.1,2,3  The pruritus associated with cholestasis varies from mild to severe and may limit normal activities, cause sleep deprivation and when unmanageable may lead to suicidal ideation.1,4 

Melatonin and its use in the treatment of tardive dyskinesia David F. McAuley, Pharm.D. GlobalRPh Inc. Introduction: Antipsychotics continue to be the mainstay of drug intervention in the management of schizophrenia, however, long-term treatment with antipsychotics is associated with a variety of movement disorders including the

David F. McAuley, Pharm.D.      Cerumen composition is based primarily on the combination of secretions of both the sebaceous and ceruminous glands located in the external ear canal and the subsequent mixing with desquamated skin.1 Cerumen also mixes with water that is trapped in the ear canal. Its consistency and appearance

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A-a gradient (Alveolar to arterial gradient) [ < BACK ] Normal: 20 - 65  //   Severe distress: >400       D.McAuley A-a gradient =  PAO2 - PaO2 PaO2 (partial pressure of O2 in the artery) --obtained from the arterial blood gases. PAO2  (partial pressure of O2 in the alveoli)-- obtained from the Alveolar Gas equation.Alveolar gas equation:

Pharmacokinetic Overview D. McAuley, GlobalRPh Inc Pharmacokinetics (Def.) Volume of distribution (VD) Bioavailability (F) Steady State Elimination rate constant Half-Life Creatinine clearance First order elimination PK properties (Overview) Mechanism of action Elimination (route) Distribution Initial Evaluation Follow-up Evaluation Adverse effects Monitoring for toxicity Serum Drug levels (Indications) Patients not requiring levels Frequency of serum levels When to draw levels.. Dosing (Step by step) Ideal body weight Adjusted body weight Kel determination Vd determination Desired Levels Time of infusion Loading

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