Medical Treatment of Dry Eye Disease
Exploring the
various topical ophthalmic options
Key points
- According to the American Academy of Ophthalmology no single test is
adequate for establishing the diagnosis of dry eye disease.
- Dry eye syndrome is one of the most common issues affecting the
general population and can be caused by several possible conditions
either separately or combined.
- With treatment, symptoms often improve, however, the disease
usually is not curable.
- Dry eye can lead to reduced visual function.
- Common symptoms include the following: burning, stinging or
itching sensation. Foreign-body sensation. Frequent
blinking. Redness. Blurry vision. Light-sensitivity. Eye
pain.
Using this
program
The program will provide a list of medications for a particular group,
common side effects, and other comments that help with selection of a
particular product.
Select any option for
additional info
Select one or more of the following OTC options:
Preservative-free
options
Other
products
Options available by prescription:
Select one or more for additional information.
RESTASIS® (cyclosporine) ophthalmic emulsion 0.05%
Xiidra (lifitegrast 5%)
LACRISERT® (hydroxypropyl cellulose) Ophthalmic Insert
References
- American Academy of Ophthalmology Basic and Clinical Science Course
Subcommittee. Basic and Clinical Science Course. External Disease and
Cornea: Section 8, 2017-2018. San Francisco, CA: American Academy of
Ophthalmology; 2017:55-56.
-
Lemp MA. Report of the National Eye Institute/Industry workshop on
Clinical Trials in Dry Eyes. CLAO J. 1995;21(4):221-232.80.
-
Fox RI. Systemic diseases associated with dry eye. Int Ophthalmol Clin.
1994;34(1):71-87.
- The Dry Eye Assessment and Management Study Research Group. n−3
Fatty Acid Supplementation for the Treatment of Dry Eye Disease. N Engl
J Med 2018; 378:1681-1690 DOI: 10.1056/NEJMoa1709691
- Baudouin C. The pathology of dry eye. Surv Ophthalmol. 2001;45(suppl
2): S211–S220.
- Lemp MA, Bron AJ, Baudouin C, et al. Tear osmolarity in the
diagnosis and management of dry eye disease. Am J Ophthalmol.
2011;151:792– 798.e1.
- Wang MTM, Tien L, Han A, et al. Impact of blinking on ocular surface
and tear film parameters. Ocul Surf. 2018.
- Mathews PM, Karakus S, Agrawal D, Hindman HB, Ramulu PY, Akpek EK.
Tear osmolarity and correlation with ocular surface parameters in
patients with dry eye. Cornea. 2017;36(11):1352-1357.
- Holland EJ, Luchs J, Karpecki PM, et al. Lifitegrast for the
treatment of dry eye disease: results of a phase III, randomized,
double-masked, placebo-controlled trial (OPUS-3). Ophthalmology.
2017;124(1):53-60.
- Mathews PM, Ramulu PY, Swenor BS, Utine CA, Rubin GS, Akpek EK.
Functional impairment of reading in patients with dry eye. Br J
Ophthalmol. 2017;101(4):481-486.
