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Creatinine Clearance – MULTI-CALC

Multiple Creatinine Clearance Methods


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Patient Name: Location:
Age: Scr: Sex:
Height: Weight:
For MDRD equation. specify race:
Is the serum creatinine (Scr) currently stable:
Select serum creatinine reference standard: [more info]

Restrictions
Restrict the maximum calculated clearance to this value:
 





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Cockcroft and Gault equation utilizing the tbw (Total body weight) to calculate an estimated CrCL  -  Cockcroft and Gault equation:


CrCl = [(140 - age) x TBW] / (Scr x 72) (x 0.85 for females)

Cockcroft and Gault equation utilizing the ibw (Ideal body weight) to calculate an estimated creatinine clearance
Cockcroft and Gault equation:


CrCl = [(140 - age) x IBW] / (Scr x 72) (x 0.85 for females)

Note: if the ABW (actual body weight) is less than the IBW use the actual body weight for calculating the CRCL.

Estimate Ideal body weight in (kg)
Males: IBW = 50 kg + 2.3 kg for each inch over 5 feet.
Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet.

Cockcroft and Gault equation utilizing the adjusted body weight to calculate an estimated creatinine clearance

CrCl = [(140 - age) x AjBW] / (Scr x 72)

Note: (Multiply result by 0.85 for females)
AjBW = adjusted body weight:
AjBW = IBW + 0.4( ABW - IBW)

Estimated IBW:
Males: IBW = 50 kg + 2.3 kg for each inch over 5 feet.
Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet.

Some studies have shown that utilizing the adjusted body weight improves accuracy compared to other commonly used equations in estimating the creatinine clearance in the elderly population.

Simplified 4-variable MDRD study formula:


GFR = 186.3 x (SCR)-1.154 x (age in years)-0.203 x 1.212 (if patient is black) x 0.742 (if female)

Key point: Early statistical analysis shows very promising results. May represent the most accurate choice of this group. This may be especially true in chronic kidney disease.

References top of page



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Creatinine Clearance – MULTI-CALC

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