Creatinine Clearance Calculator
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Patient Name:
Location:
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Age:
Scr:
Sex:
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Select serum creatinine reference standard: [more info]
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Height:
Weight:
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Is the serum creatinine (Scr) currently stable:
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Restrict the maximum calculated clearance to this value:
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Creatinine Clearance methods
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Cockcroft and Gault equation utilizing the tbw (Total body
weight) to calculate an estimated CrCL
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Cockcroft and Gault equation:
CrCl = [(140 - age) x TBW] / (Scr x 72) (x 0.85 for females) |
Cockcroft and Gault equation utilizing the ibw (Ideal body weight) to
calculate an estimated creatinine clearance
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Cockcroft and Gault equation:
CrCl = [(140 - age) x IBW] / (Scr x 72) (x 0.85 for females)
Note: if the ABW (actual body weight) is less than the IBW use the
actual body weight for calculating the CRCL.
Estimate Ideal body weight in (kg)
Males: IBW = 50 kg + 2.3 kg for each inch over 5 feet.
Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet. |
Cockcroft and Gault equation utilizing the adjusted body weight to calculate
an estimated creatinine clearance.
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CrCl = [(140 - age) x AjBW] / (Scr x 72)
Note: (Multiply result by 0.85 for females)
AjBW = adjusted body weight:
AjBW = IBW + 0.4( ABW - IBW)
Estimated IBW:
Males: IBW = 50 kg + 2.3 kg for each inch over 5 feet.
Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet.
Some studies have shown that utilizing the adjusted body weight improves
accuracy compared to other commonly used equations in estimating the
creatinine clearance in the elderly population.
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References
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- Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum
creatinine. Nephron 1976;16(1):31-41
- Davis GA, Chandler MH. Comparison of creatinine clearance estimation
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- Dawson-Saunders B, Trapp RG. Basic and Clinical Biostatistics. 2nd ed.
Norwalk, CT: Appleton & Lange; 1994.
- Demirovic JA, Pai AB, Pai MP. Estimation of creatinine clearance in
morbidly obese patients. Am J Health Syst Pharm 2009; 66: 642-648
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- Dooley MJ, Singh S, Rischin D. Rounding of low serum creatinine levels
and consequent impact on accuracy of bedside estimates of renal
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14997195 DOI: 10.1038/sj.bjc.6601641]
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estimating creatinine clearance are inadequate for elderly debilitated
nursing home patients. J Am Geriatrics Soc 1998;36:437-41.
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requirements in patients with low serum creatinine concentrations. Am J
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collected. Lancet 1971;1:975-6.
- Levey AS, Greene T, Kusek JW, et al. A simplified equation to predict
glomerular filtration rate from serum creatinine (Abstr) J Am Soc Nephrol
2000;(11):155A
- Levey AS, Greene T, Schluchter MD, et al. Glomerular filtration rate
measurements in clinical trials. Modification of Diet in Renal Disease Study
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progression of renal disease. Am J Kidney Dis 1993;22(1):207-14
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glomerular filtration rate from serum creatinine: a new prediction equation.
Modification of Diet in Renal Disease Study Group. Ann Intern Med
1999;130(6):461-70
- Rhodes RS, Sims PJ, Culbertson VL et al. Accuracy of creatinine
clearance estimates in geriatric males with elevated serum creatinine
clearance. J Geriatric Drug Ther 1991;5:31-45.
- Smythe M, Hoffman J, Kizy K et al. Estimating creatinine clearance in
elderly patients with low serum creatinine concentrations. Am J Hosp Pharm
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- Wilhelm SM, Kale-Pradhan PB. Estimating creatinine clearance: a
meta-analysis. Pharmacotherapy 2011; 31: 658-664 [PMID: 21923452 DOI:
10.1592/phco.31.7.658]
- Winter MA, Guhr KN, Berg GM. Impact of various body weights and
serum creatinine concentrations on the bias and accuracy of the
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22576791 DOI: 10.1002/j.1875-9114.2012.01098.x]
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