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Corticosteroid -Glucocorticoid Conversion based on potency
Corticosteroid -Glucocorticoid Conversion based on potency
Corticosteroid converter
The potency and duration of action of the various glucocorticoids can vary greatly. Oral potency may be less than parenteral potency because significant amounts (up to 50% in some cases) may not reach the circulation. Cortisol is the standard of comparison for glucocorticoid potency.
Select a steroid to convert
cortisone
hydrocortisone
prednisone
prednisolone
triamcinolone
methylprednisolone
dexamethasone
betamethasone
Dose (mg):
Select new steroid
cortisone
hydrocortisone
prednisone
prednisolone
triamcinolone
methylprednisolone
dexamethasone
betamethasone
Conversion Data
Glucocorticoid
Approximate Equivalent dose (mg)
Half-life (Biologic) hours
Short-Acting
Cortisone
25
8-12
Hydrocortisone
20
8-12
Intermediate-Acting
Methylprednisolone
4
18-36
Prednisolone
5
18-36
Prednisone
5
18-36
Triamcinolone
4
18-36
Long-Acting
Betamethasone
0.6 - 0.75
36-54
Dexamethasone
0.75
36-54
References
:
Dixon JS. Second-line Agents in the Treatment of Rheumatic Diseases. Informa Health Care, 1991. (456).
Meikle AW and Tyler FH. Potency and duration of action of glucocorticoids. Am J of Med 1977;63;200.
Webb R, Singer M. Oxford Handbook of Critical Care. Oxford ; New York : Oxford University Press, 2005.