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Clinical pharmacology

Initial U.S. Approval:  2015
Mechanism of Action: Uridine triacetate is an acetylated form of uridine. Following oral administration, uridine triacetate is deacetylated by nonspecific esterases present throughout the body, yielding uridine in the circulation.
XURIDEN provides uridine in the systemic circulation of patients with hereditary orotic aciduria who cannot synthesize adequate quantities of uridine due to a genetic defect in uridine nucleotide synthesis.

Indications and usage 

INDICATIONS AND USAGE:  XURIDEN™ is indicated for the treatment of hereditary orotic aciduria.

Dosage and administration 

Drug UPDATES: XURIDEN ™ - uridine triacetate granule
[Drug information  /  PDF]     Click link for the latest monograph
Dosing:  Click (+) next to Dosage and Administration section (drug info link)

How supplied

HOW SUPPLIED: Oral granules: 2 grams of orange-flavored oral granules (95% w/w) in single-use packets


[Drug information  /  PDF]     Click link for the latest monograph


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