| BOXED WARNING:
WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS
Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. NUPLAZID is not approved for the treatment of patients with dementia-related psychosis unrelated to the hallucinations and delusions associated with Parkinson's disease psychosis
Initial U.S. Approval: 2016
Mechanism of Action:
The mechanism of action of pimavanserin in the treatment of hallucinations and delusions associated with Parkinson's disease psychosis is unknown. However, the effect of pimavanserin could be mediated through a combination of inverse agonist and antagonist activity at serotonin 5-HT2A receptors and to a lesser extent at serotonin 5-HT2C receptors.
| INDICATIONS AND USAGE:
NUPLAZID is an atypical antipsychotic indicated for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis.
| Drug UPDATES: NUPLAZID™ (pimavanserin) tablets
[Drug information / PDF]
Package insert - Dosing: Click (+) next to Dosage and Administration section (drug info link)
DOSAGE AND ADMINISTRATION
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