Mast cell stabilizers
Cromolyn sodium (intal ®)
| Inhalation: May be used as an adjunct in the prophylaxis of allergic disorders, including asthma; prevention of exercise-induced bronchospasm
For chronic control of asthma, taper frequency to the lowest effective dose (ie, 4 times/day to 3 times/day to twice daily):
Nebulization solution: Children >2 years and Adults: Initial: 20 mg 4 times/day; usual dose: 20 mg 3-4 times/day
Children >/= 12 years and Adults: Initial: 2 inhalations 4 times/day; usual dose: 2-4 inhalations 3-4 times/day
Prevention of allergen- or exercise-induced bronchospasm: Administer 10-15 minutes prior to exercise or allergen exposure but no longer than 1 hour before:
Nebulization solution: Children >2 years and Adults: Single dose of 20 mg
Metered spray: Children >5 years and Adults: Single dose of 2 inhalations
Solution for nebulization, as sodium (Intal®): 20 mg/2 mL (60s, 120s)
Nedocromil (tilade ®)
National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
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