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Drug / Food Interactions

Drug Tables

Drug food Interactions
Medications which should be taken on an
EMPTY stomach
Alendronate
(Fosamax)		 Ampicillin Astemizole Bethanechol
Bisacodyl Captopril
(Take 1 hour before meals)		 Cefibuten
(Cedax)		 Cilostazol
(Pletal)
Demeclocycline Dicloxacillin Didanosine
(Videx)		 Etidronate
(Didronel)
Felodipine
(Plendil)		 Indinavir
(Crixivan)		 Lansoprazole
(take before eating)		 Levothyroxine
loratadine
(Claritin)		 loracarbef
(Lorabid)		 Methotrexate Moexipril
(Univasc)
Mycophenolate
(Cellcept)		 Omeprazole
Take before eating		 Oxacillin Penicillamine
Perindopril
(Aceon)		 Repaglinide
(Prandin)		 Rifampin Rifabutin
(Mycobutin)
Riluzole
(Rilutek)		 Roxithromycin (take at least 15 minutes before or after a meal) Sucralfate
(Carafate)		 Sulfamethoxazole - trimethoprim (Bactrim)
Sulfadiazine Tetracycline
(Do not take with milk or other dairy products)		 Tolcapone
(Tasmar)		 Zafirlukast (Accolate)
Zalcitabine
(Hivid)
Medications which should be
Taken with FOOD
Allopurinol
(take after meal)		 Atovaquone
(Mepron)		 Augmentin Aspirin
Amiodarone
(Cordarone)		 Baclofen
(Lioresal)		 Bromocriptine
(Parlodel)		 clofazimine
(Lamprene)
Carvedilol
(Coreg)		 Carbamazepine
(Tegretol)		 Chloroquine Cimetidine
(Tagamet)
Cefpodoxime
(Vantin)		 Diclofenac
(Voltaren_		 Divalproex sodium
(Depakote)		 Doxycycline
Felbamate
(Felbatol)		 fenofibrate
(TriCor)		 Fiorinal Fludrocortisone
fenoprofen Griseofulvin glyburide (take with breakfast) Hydrocortisone
Hydroxychloroquine
(Plaquenil)		 Indomethacin Iron preparations (Take between meals--if GI upset occurs take with food) Itraconazole capsules
Ketorolac Lithium Metronidazole Misoprostol
(Cytotec)
methanamine mebendazole methylprednisolone naltrexone
Naproxen Nelfinavir
(Viracept)		 Nitrofurantoin Niacin
Olsalazine Perphenazine Pentoxifylline Pergolide
Piroxicam Potassium salts Prednisone Procainamide
Ritonavir
(Norvir)		 Salsalate Saquinavir Sevelamer
(Renagel)
Spironolactone Sulfasalazine Sulfinpyrazone Sulindac
Ticlopidine Tolmetin Trazodone Troglitazone
Valproic acid
Drug - grapefruit interactions:
Drugs which may exhibit increased serum concentrations based on this interaction
amiodarone astemizole alprazolam atorvastatin
benzodiazepines buspirone carbamazepine carvedilol
cerivastatin cilostazol clarithromycin Clomipramine
codeine cyclosporine dapsone dextromethorphan
diazepam diltiazem estrogens erythromycin
felodipine fentanyl finasteride haloperidol
indinavir lercanidipine lidocaine lovastatin
midazolam methadone nelfinavir nifedipine
nicardipine nimodipine nisoldipine nitrendipine
ondansetron paclitaxel progestins progesterone
quinidine ritonavir salmeterol saquinavir
simvastatin tacrolimus trazodone triazolam
vincristine zaleplon zolpidem
Note: there may be omissions on this list. Absence of a drug
does not necessarily indicate that the drug lacks this potential
interaction.
Warfarin - food Interactions 
Web site link
Management of Dietary Interactions and Vitamin K: dietary consistency is the key to maintaining a sustained, stable response during warfarin therapy. Patients should be aware of vitamin K content in common foods, particularly foods high in vitamin K (green leafy vegetables (broccoli, Brussel sprouts, turnip greens, kale, spinach, beet greens), Cauliflower , legumes, mayonnaise, canola and soybean oils), and should maintain a consistent amount of these foods in their diet.
The following foods should be avoided or limited, since they also can effect warfarin therapy:  caffeinated beverages (cola, coffee, tea, hot chocolate, chocolate milk).
Alcohol intake greater than 3 drinks daily can increase the effect of Coumadin. As long as alcohol intake does not exceed 3 drinks daily, clotting times should not be affected. This amount of alcohol is present in 12 ounces of table wine or three 12  ounce beers. (Acute binges can raise INR. Chronic alcohol ingestion may decrease INR. )
Herbal supplements can affect bleeding time.  Coenzyme Q10 is an herbal supplement whose chemical structure is similar to vitamin K, so it has the potential to affect bleeding time.  Herbal teas: green tea, buckeye, horsechestnut, tonka, bean, meliot, and woodruff.  Other examples include: feverfew, garlic, and ginseng.  Herbal medications should either be avoided or used consistently while on warfarin therapy

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.

Drug / Food Interactions

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