Corticosteroids (intra-articular)

Depo-medrol (methylprednisolone acetate)

Intra-articular
Administer every 1 to 5 weeks.
Large joints (knee,ankle,shoulder): 20-80mg.
Medium joints (elbow,wrist): 10-40 mg intrasynovial.
Small joints(fingers etc): 4-10mg.

Intralesional (acetate):
20-60 mg every 1-5 weeks

Not for IV use. Routes: IM, intrasynovial, intralesional, soft-tissue.

Supplied:
Injection, suspension, as acetate (Depo-Medrol®): 20 mg/mL (5 mL); 40 mg/mL (5 mL); 80 mg/mL (5 mL) [contains benzyl alcohol; strength expressed as base]

Triamcinolone acetonide (kenalog)

(Kenalog-10:10mg/ml)
(Kenalog-40: 40mg/ml):

Kenalog-10: May be given intradermal or intra-articular.
Small joints: 2.5 to 5mg.
Large joints: 5 to 15mg.

Kenalog-40: May be given IM (usual range: 40-80mg) or Intra-articular
(Smaller joints): 2.5- 5mg;
(large joints): 40mg.

Not for IV use.

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
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