Use the renal measure and units named by this source. Confirm product, indication, age, stable versus changing kidney function, and exact dialysis modality. The selected summary is not a complete prescribing monograph. Renal method and dosing checklist
Choose a source to read (3)
Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.
1 additional source qualifications - review before use
Select the intended schedule and indication first. Once-daily ED/BPH and pulmonary hypertension have different instructions.
Before applying: Apply only to the stated formulation, indication and renal population.
Also check: Cialis as needed - product and source limitations
Official source
Cialis as needed - labeled renal guidance
Renal action and limits
Tadalafil (Cialis), adult oral tablets for as-needed erectile dysfunction Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Action or finding
For as-needed ED at CrCl 30-50 mL/min, start with 5 mg up to once daily; 10 mg is limited to once every 48 hours. Below 30 or on HD, do not exceed 5 mg every 72 hours.
Limits and monitoring
Select the intended schedule and indication first. Once-daily ED/BPH and pulmonary hypertension have different instructions.
Before use
Apply only to the stated formulation, indication and renal population.
DailyMed SPL version 52, effective 2026-06-03; posted Jun 10, 2026 | Selected sections checked 2026-11-07. Independent clinical review pending.
Tadalafil (Cialis), adult oral tablets for as-needed erectile dysfunction
Renal measure
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source revision
DailyMed SPL version 52, effective 2026-06-03; posted Jun 10, 2026
Retrieved
2026-11-07 (not the revision date)
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Renal guidance: 2.6 and 8.7
For as-needed ED at CrCl 30-50 mL/min, start with 5 mg up to once daily; 10 mg is limited to once every 48 hours. Below 30 or on HD, do not exceed 5 mg every 72 hours. Select the intended schedule and indication first. Once-daily ED/BPH and pulmonary hypertension have different instructions.
Source revision: DailyMed SPL version 52, effective 2026-06-03; posted Jun 10, 2026 | Retrieved: 2026-11-07. Retrieval date is not the revision date.
All sources, comparison tools and evidence navigation
Source-specific interpretation
What the dialysis evidence actually supports
Removal information alone does not define a maintenance dose, supplemental dose or dialysis schedule. A reported regimen still requires its product, indication, renal measure and dialysis assumptions to match the patient.
Cialis as needed - labeled renal guidance
Source retrieved 2026-11-07 - confirm current applicability
These manual classifications apply only to the identified selected sections, not every retained source or the entire prescribing information. They are not dosing clearance.
Source-first renal review
Evidence sources and renal implications
Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.
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Share a reproducible source review
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Source-by-source comparison
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Renal-context checklist: population, kidney trend and dialysis
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Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.
These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.
Source scope / renal recommendation differences
Cialis as needed - product and source limitations
Select the intended schedule and indication first. Once-daily ED/BPH and pulmonary hypertension have different instructions.
How to use this: Apply only to the stated formulation, indication and renal population.
Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.
Independent clinical review is pending. These selected summaries are not an approved institutional dosing protocol. Confirm the exact product, the complete current source and local policy before use.
Official source
Cialis as needed - labeled renal guidance
Tadalafil (Cialis), adult oral tablets for as-needed erectile dysfunction
Method: Creatinine clearance (CrCl), mL/min; use the product-specific calculation
No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.
Compare or copy source versions
All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.
Historical source content is not a current prescription. Original GlobalRPh recommendations are preserved, not automatically certified as current. Product-label and professional additions below are separately attributed. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Important source distinctions
As-needed ED source, not daily ED/BPH or pulmonary-hypertension dosing. The missing severe-impairment interval must not be inferred.
Locally stored source content
Original GlobalRPh protocol
Clinical facts and comments transcribed into a structured reading format. Read the original source for its complete context: https://globalrph.com/renal/tadalafil/
Usual Dosing (Adults)
10 mg orally before anticipated sexual activity, as a single as-needed dose no more than once daily; range 5-20 mg. Adjust for concomitant alpha blocker or CYP3A4 inhibitor.
CrCl above 50 mL/min: no change. Source band 31-50: initially 5 mg, with a maximum 10 mg no more frequently than every 48 hours. Below 30 or HD: maximum 5 mg. The original text does not supply a dose interval for the below-30/HD group or explicitly assign exactly 30.
For as-needed ED at CrCl 30-50 mL/min, start with 5 mg up to once daily; 10 mg is limited to once every 48 hours. Below 30 or on HD, do not exceed 5 mg every 72 hours. Select the intended schedule and indication first. Once-daily ED/BPH and pulmonary hypertension have different instructions.
RDM73-cialis-official-1 · Source locator: Renal guidance: 2.6 and 8.7
GlobalRPh RX List / product-label mirror · Tadalafil (Cialis), adult oral tablets for as-needed erectile dysfunction
Renal method: Use the renal measure explicitly present in the RX passage. Source date: Mirror revision not established in the reviewed passage. Retrieved: 2026-11-07
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.
The original individual GlobalRPh pages commonly cite NIH/NLM DailyMed and instruct readers to review the applicable package insert for updates. That historical reference is preserved as context; it is not counted as an independently retrieved current label.
