GlobalRPh Renal Dosing Masterv6.6
GlobalRPh source record

Tadalafil - as-needed erectile dysfunction

GlobalRPh source pageBase record retrieved 2026-09-05See the evidence for this drug1 sources available - open source summaries, references and comparisons
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Renal measure
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As-needed ED source, not daily ED/BPH or pulmonary-hypertension dosing. The missing severe-impairment interval must not be inferred.

Usual Dosing (Adults)

10 mg orally before anticipated sexual activity, as a single as-needed dose no more than once daily; range 5-20 mg. Adjust for concomitant alpha blocker or CYP3A4 inhibitor.

Renal Dosing

CrCl above 50 mL/min: no change. Source band 31-50: initially 5 mg, with a maximum 10 mg no more frequently than every 48 hours. Below 30 or HD: maximum 5 mg. The original text does not supply a dose interval for the below-30/HD group or explicitly assign exactly 30.

Hemodialysis

Maximum 5 mg; no frequency is supplied in the original dialysis section.

Source revision: Historical source; revision not established here | Retrieved: 2026-09-05. Retrieval date is not the revision date.

Source: https://globalrph.com/renal/tadalafil/

Scope: Preserved historical source; no fresh clinical approval GlobalRPh v6.6.

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Retrieved: 2026-09-05

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Original content / product scope
Historical source content is not a current prescription. Original GlobalRPh recommendations are preserved, not automatically certified as current. Product-label and professional additions below are separately attributed. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Important source distinctions

As-needed ED source, not daily ED/BPH or pulmonary-hypertension dosing. The missing severe-impairment interval must not be inferred.

Locally stored source content

Original GlobalRPh protocol

Clinical facts and comments transcribed into a structured reading format. This is not a byte-for-byte HTML archive. Original source: https://globalrph.com/renal/tadalafil/

Usual Dosing (Adults)

10 mg orally before anticipated sexual activity, as a single as-needed dose no more than once daily; range 5-20 mg. Adjust for concomitant alpha blocker or CYP3A4 inhibitor.

GRPH-tadalafil-01 · Source section: Usual Dosing (Adults)Renal section finder

Renal Dosing

CrCl above 50 mL/min: no change. Source band 31-50: initially 5 mg, with a maximum 10 mg no more frequently than every 48 hours. Below 30 or HD: maximum 5 mg. The original text does not supply a dose interval for the below-30/HD group or explicitly assign exactly 30.

GRPH-tadalafil-02 · Source section: Renal DosingRenal section finder

Hemodialysis

Maximum 5 mg; no frequency is supplied in the original dialysis section.

GRPH-tadalafil-03 · Source section: HemodialysisRenal section finder

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 0 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/renal/tadalafil/
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
globalrph individual
Local text SHA-256
ba85ee8cdbaebda63f83670621f9c970feecb5b6446ca6ee60fc2a810c2b1dff
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

The original individual GlobalRPh pages commonly cite NIH/NLM DailyMed and instruct readers to review the applicable package insert for updates. That historical reference is preserved as context; it is not counted as an independently retrieved current label.

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