GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Methylnaltrexone (RELISTOR)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

Relistor

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Renal guidance at a glance

Confirm the product, indication and renal measure. The selected summary is not a complete prescribing monograph.

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Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

Rxlist source

GlobalRPh RX List - Relistor

Product / population
Adult opioid-induced constipation. Oral and subcutaneous regimens remain explicitly separate.
Renal measure
CrCl by Cockcroft-Gault, mL/min.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

For CrCl below 60 mL/min, chronic non-cancer pain: oral tablets 150 mg each morning, or injection 6 mg subcutaneously once daily. For advanced illness: subcutaneous dosing every other day as needed is 0.075 mg/kg below 38 kg; 4 mg at 38 to less than 62 kg; 6 mg at 62 to 114 kg; or 0.075 mg/kg above 114 kg. These advanced-illness doses are not the chronic non-cancer pain schedule. Use the vial when a prefilled syringe does not match the prescribed dose.

Source revision: Revised May 2024 | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/relistor-drug/

Scope: Locally imported selected source sections; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

Full source card / provenance

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Source-first renal review

Evidence sources and renal implications

Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.

GlobalRPh RX List

GlobalRPh RX List - Relistor

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Adult opioid-induced constipation. Oral and subcutaneous regimens remain explicitly separate.

Renal method: CrCl by Cockcroft-Gault, mL/min.
Retrieved: 2026-09-07

Read local renal resultOpen original reference

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

Product / population check

Confirm the exact formulation before using a renal source

These links compare product identities, not interchangeable doses. A selected summary is not a complete prescribing monograph.

Source-quality holds
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Search the stored clinical text

Locate a word or phrase within this drug's source summaries. Choose all sources or one source to focus the search. The selection never hides warnings or source text, changes a dose, or proves that a renal finding is absent.

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All source summaries, original wording and provenance
Before applying a renal protocol

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No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.

Share a reproducible source review

Choose sources below, then open a print-ready comparison with product scope, renal method, dates and cautions. Links can pin the exact local cards; they never contain patient values or choose a dose.

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Jump to renal guidanceClinician guide

Only one eligible source version is stored here. No second source is inferred from a reference link. Independent corroboration is still needed.

Build a source-review outline for documentation

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Renal-context checklist: population, kidney trend and dialysis

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Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

Go directly to the relevant source section

Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

Compare or copy source versions

All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.

Original content / product scopeGlobalRPh RX List - Relistor
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/relistor-drug/

Product and population scope

Adult opioid-induced constipation. Oral and subcutaneous regimens remain explicitly separate.

RDM33-SCOPE-methylnaltrexone-relistor-C1 · Source section: Exact product identity and selected populationRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - Relistor

Open original reference

Open / share this exact local source

GlobalRPh-hosted RX List · Adult opioid-induced constipation. Oral and subcutaneous regimens remain explicitly separate.

Renal method: CrCl by Cockcroft-Gault, mL/min.
Source date: Revised May 2024
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Locally imported selected source sections; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

For CrCl below 60 mL/min, chronic non-cancer pain: oral tablets 150 mg each morning, or injection 6 mg subcutaneously once daily. For advanced illness: subcutaneous dosing every other day as needed is 0.075 mg/kg below 38 kg; 4 mg at 38 to less than 62 kg; 6 mg at 62 to 114 kg; or 0.075 mg/kg above 114 kg. These advanced-illness doses are not the chronic non-cancer pain schedule. Use the vial when a prefilled syringe does not match the prescribed dose.

RDM33-rxlist-methylnaltrexone-relistor-C1 · Source locator: Dosage in patients with renal impairment, Table 2.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/relistor-drug/
Retrieved
2026-09-07
Renal-function method
CrCl by Cockcroft-Gault, mL/min.
Source date/version
Revised May 2024
Hash meaning
SHA-256 of the local authored summary only; original HTML/PDF/SPL bytes are not bundled or hashed.
Local summary SHA-256
b247885fd18be730b164cbd3e60fc4c300377e24148975dcceda08d93042a3d8

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/relistor-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
ee7087a45b9b87b9fdb5e7b8640608fe18a0524007f09dff809acb71be72c922
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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