| Septic Arthritis |
Possible therapeutic alternatives |
| Septic arthritis – native joint |
S. aureus
Strept
Gram negative bacilli |
MRSA unlikely:
[Nafcillin 2 grams ivpb q4h or Oxacillin 2 grams ivpb q4h] PLUS Ceftriaxone 2 grams ivpb q24h.
or
Vancomycin (patient specific dosage regimen) +
Ceftriaxone 1-2g q24h |
|
| Septic arthritis– prosthetic joint |
S. epidermidis,
S. aureus
Gram negative bacilli
P. aeruginosa |
| Vancomycin (patient specific dosage regimen) + Cefepime 2 gm IV q8-12h. |
|
| Gonococcal arthritis/ disseminated gonococcal infection |
|
| IV: Ceftriaxone 1g IV or IM q24h or Cefotaxime 1g IV q8h or ceftizoxime 1g IV q8h.
Oral: Cefixime or cefpodoxime 400mg orally twice daily.
[Also treat empirically for concomitant chlamydia infection: doxycycline 100 mg twice daily x 7 days or, if pregnant, azithromycin 1000mg orally x 1. ] |
|
