Pyelonephritis

Pyelonephritis
Duration of therapy: Usually for 14 days. If recurrent or failure after 14 days, treat for 6 weeks.

Possible therapeutic alternatives

Uncomplicated
(Outpatient treatment).

Therapy length:
14 days

Ciprofloxacin 500mg orally twice daily OR.

Norfloxacin 400mg orally twice daily OR

Ofloxacin 200- 400mg orally twice daily OR

Levofloxacin 750mg orally once daily for 14 days OR

Augmentin 875/125 mg orally twice daily or 500/125mg three times daily

Hospitalized patient (recommend IV therapy until afebrile. Usually 24-48h, then switch to oral therapy

Ciprofloxacin 200 to 400mg IV every 12 hours OR

Levofloxacin 500mg IV once daily OR

[Ampicillin 1-2 gram IV every 6 hours + gentamicin IV] OR

Ceftriaxone 2 grams IV once daily for 14 days OR

Ampicillin-sulbactam 1.5 to 3 grams IV every 6 hours
OR
Piperacillin-tazobactam 3.375 grams IV q6h for 14 days.

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