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Possible therapeutic alternatives
Note: antibiotic therapy is usually reserved for severe acute exacerbations.

Bronchitis: Acute bacterial exacerbation

Acute bacterial exacerbation (Usually adult smoker with COPD).

Therapy length: generally 5 - 14 days

Common pathogens

Amoxicillin 500mg orally three times daily OR
Doxycycline 100mg orally twice daily  OR
Bactrim DS orally twice daily x 5 days


Augmentin 875/125 mg orally twice daily or  500/125mg three times daily x 7 days OR
Azithromycin 500mg orally x 1 then 250mg  once daily for 4 days   OR 
Clarithromycin 500mg po q12h x 3 to 10 days or Biaxin XL ®: 1000mg po qd. OR
Cefdinir (Omnicef) 300 mg po q12h or 600 mg po q24h  OR
Ceftin (cefuroxime oral) 250-500mg orally twice daily  OR
Cefprozil (Cefzil) 500 mg orally twice daily OR Cefpodoxime (Vantin) 200-400 mg orally twice daily OR
Levofloxacin 500mg orally once daily OR
Moxifloxacin 400mg po qd 

Viral - Influenza (should be within 48 hours of onset): 
rimantadine (Flumadine®) 100 mg orally twice daily x 5 days [RENAL] In patients with severe renal failure (CrCl </= 10 ml/min) and elderly nursing home patients, a dose reduction to 100 mg daily is recommended. 
oseltamivir (Tamiflu®) 75mg orally twice daily x 5 days [Renal Dosing: If crcl< 30 ml/min: give 75mg orally once daily x 5 days. Supplied: [75mg cap]



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