Age related changes in absorption

Absorbtion
Many changes occur in the gastrointestinal tract with age:
(1) Increased gastric emptying time(2) Decreased salivary flow(3) Decreased absorptive capacity of intestinal cells

(4) Decreased gastric acid secretion

(5) Reduced gastrointestinal motility.

(6)Reduced splanchnic blood flow.
Despite these changes, there is little change in drug absorption with age. The rate of absorption may change, but the extent does not. It important to note that any adverse effect observed with drug therapy cannot be attributed to altered drug absorption with age, because no clinically important changes occur.

 

 

Geriatric issues
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Age related changes in absorption