[>30 ml/min]: No changes [15-30]: 100 mg q18h or 50mg q12h. [<15]: 100 mg q24h or avoid use.
Hemodialysis
Avoid use or give 100mg q24h (on dialysis days give dose after dialysis).
Reference(s)
National Institutes of Health, U.S. National Library of Medicine, DailyMed Database. Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates. A local search option of this data can be found here.