Emtricitabine

Usual Dosing (Adults)

Recommended Dose
EMTRIVA may be taken without regard to food.

Adult Patients (18 years of age and older)
EMTRIVA capsules: one 200 mg capsule administered once daily orally.
EMTRIVA oral solution: 240 mg (24 mL) administered once daily orally.

Pediatric Patients (0–3 months of age)
EMTRIVA oral solution: 3 mg/kg administered once daily orally.

Pediatric Patients (3 months through 17 years)
EMTRIVA oral solution: 6 mg/kg up to a maximum of 240 mg (24 mL) administered once daily orally.
EMTRIVA capsules: for children weighing more than 33 kg who can swallow an intact capsule, one 200 mg capsule administered once daily orally.

Renal Dosing

Dose Adjustment in Adult Patients with Renal Impairment

	Creatinine Clearance (mL/min)
Formulation	>/=50 mL/min	30–49 mL/min	15–29 mL/min	<15 mL/min or on hemodialysis*
*Hemodialysis Patients: If dosing on day of dialysis, give dose after dialysis
Capsule (200 mg)	200 mg every 24 hours	200 mg every 48 hours	200 mg every 72 hours	200 mg every 96 hours
Oral Solution (10 mg/mL)	240 mg every 24 hours (24 mL)	120 mg every 24 hours (12 mL)	80 mg every 24 hours (8 mL)	60 mg every 24 hours (6 mL)

Although there are insufficient data to recommend a specific dose adjustment of EMTRIVA in pediatric patients with renal impairment, a reduction in the dose and/or an increase in the dosing interval similar to adjustments for adults should be considered.

Hemodialysis

See above

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
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