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Infectious Disease
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Gangrene
Gangrene
Gangrene
Gangrene
Length of therapy: 10-28 days
Possible therapeutic alternatives
Gas Gangrene
Common pathogens
Clindamycin
600 mg IV q6h or 900mg IV q8h
PLUS
Penicillin G
2-4 million units IV q4h
PLUS
Surgical debridement
[
Ceftriaxone
2grams IV q12h or
Cefotaxime
2-4 gm IV q8h ] +/-
Clindamycin
600 mg IV q6h
Penicillin Allergy:
Clindamycin
600 mg IV q6h or 900mg IV q8h
Chloramphenicol: 1 gm IV q6h
Erythromycin
1 gram IV q6h
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