Pharmacokinetics for pediatrics (dosing by levels full version)
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Co-developed with Clinical Pharmacy Staff, Dayton Children’s Hospital, One Children’s Plaza |
Patient:
Location:
Gender: Drug:
Weight:
Peak level obtained: mcg/mL
Number hours post dose:
Trough level obtained:
mcg/mL
Number hours post dose:
Current dose being given: mg
Current dosing interval:
Current infusion time (hrs):
(Note: program adds 0.5
hours to infusion time to account for a longer distribution
phase in neonates)
Desired peak:
mcg/ml
Desired trough:
mcg/mL
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Sample problem to
aid filling out the table above
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Patient is receiving Gentamicin
120mg IVPB q8h. Infusion time is 30 minutes. A peak is drawn 1 hour after
the start of the infusion and a trough is drawn 5 hours after the
start
of the infusion (note the entries below). The program will take into
account the infusion time when calculating the actual peak (do not
subtract the infusion time from the number of hours post dose). This
program assumes that information provided is based on steady state. If you
were to calculate these values by hand, the actual Cmax would occur at the
end of the infusion. In this example (t)= 1- 0.5 = 0.5. The Cmin
calculation would use a time value of (8 - 5 = 3 hours). |
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