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Stavudine - Zerit ® - Renal Dosing

Usual Dosing (Adults)

HIV infection:
>60kg: 40mg orally q12h 
<60kg: 30mg orally q12h.

Renal Dosing

dialysis [CRCL >50]: No changes

[26-50]: 
>60 kg: 20 mg q12h.
<60 kg: 15 mg q12h.

[10-25]: 
>60 kg: 20mg q24h.
<60kg: 15 mg q24h.

[<10 – not on hemodialysis]: Insufficient data exists

Hemodialysis

dialysis Hemodialysis: 
>60 kg: 20mg q24h (on dialysis days, schedule dose after dialysis)

<60kg: 15 mg q24h. (on dialysis days, schedule dose after dialysis)

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer
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