Edema (CHF, hepatic cirrhosis, or nephrotic syndrome): initial daily dosage of
100 mg given in single or divided doses ( range: 25 to 200 mg daily). When given
as the sole agent for diuresis, should be continued for at least five days at
the initial dosage level, after which it may be adjusted to the optimal
therapeutic or maintenance level administered in either single or divided daily
Hypertension: initial dosage of 50 to 100 mg given in either single or divided
doses. Aldactone may also be given with diuretics which act more proximally in
the renal tubule or with other antihypertensive agents. Treatment with Aldactone
should be continued for at least two weeks, since the maximum response may not
occur before this time.
Hypokalemia: Dosage ranging from 25 mg to 100 mg daily is useful in treating a
diuretic-induced hypokalemia, when oral potassium supplements or other
potassium-sparing regimens are considered inappropriate.
Aldactone is contraindicated for patients with anuria, acute renal
insufficiency, significant impairment of renal excretory function, or
[>50 ml/min]: No changes
[10-50]: Give q12-24 hours.
[<10 ml/min]: Avoid use.
National Institutes of Health, U.S. National Library of Medicine,
DailyMed Database. Provides access to the latest drug monographs submitted to the
Food and Drug Administration (FDA). Please review the latest applicable package insert for
additional information and possible updates. A local search
option of this data can be found here.
The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical
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