Meropenem

Usual Dosing (Adults)

Usual: 1 gram IV q8h.
Complicated skin/skin structure infections: 500 mg IV q8h.
Intra-abdominal infections: 1 gram IV q8h.
Meningitis: 2 gram IV q8h.

Renal Dosing

[CRCL >50]: no change

[26-50]: Usual: 1 gram q12h.
(UTI, skin/ skin structure infections): 500mg q12h

[10-25]: Usual: 500 mg q12h.
(UTI, skin/ skin structure infections): 250mg q12h

[<10]: Usual: 500mg q24h.
(UTI, skin/ skin structure infections): 250mg q24h

Hemodialysis

Package insert:
There is inadequate information regarding the use of MERREM I.V. in patients on hemodialysis.

There is no experience with peritoneal dialysis.

Other:

Hemodialysis:
500mg q24h + 500mg after each HD

PD:
500mg q24h.

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates. A local search option of this data can be found here.