Type 2 Diabetes Mellitus - BYETTA is indicated as an adjunct to diet and
exercise to improve glycemic control in adults with type 2 diabetes mellitus.
BYETTA should be initiated at 5 mcg administered twice daily at any time within
the 60-minute period before the morning and evening meals (or before the two
main meals of the day, approximately 6 hours or more apart). BYETTA should not
be administered after a meal. Based on clinical response, the dose of BYETTA can
be increased to 10 mcg twice daily after 1 month of therapy. Initiation with 5
mcg reduces the incidence and severity of gastrointestinal side effects. Each
dose should be administered as a subcutaneous (SC) injection in the thigh,
abdomen, or upper arm. Do not mix BYETTA with insulin. Do not transfer BYETTA
from the pen to a syringe or a vial. No data are available on the safety or
efficacy of intravenous or intramuscular injection of BYETTA.
Use BYETTA only if it is clear, colorless and contains no particles.
[>30 ml/min]: No changes
[<30]: Not recommended
National Institutes of Health, U.S. National Library of Medicine,
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Food and Drug Administration (FDA). Please review the latest applicable package insert for
additional information and possible updates. A local search
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The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical
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