GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Tranexamic acid - CYKLOKAPRON IV injection

Local official-label summaryBase record retrieved 2026-09-09See the evidence for this drug2 sources available - open source summaries, references and comparisons

CYKLOKAPRON / tranexamic acid IV / tranexamic acid injection

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Renal guidance at a glance

Cautions / source differences (1)
Review first - source-specific qualification

IV-only administration and an overlapping printed boundary

The official renal table repeats an exact creatinine value in adjacent rows. Its doses are scoped to the hemophilia/tooth-extraction indication.

Before applying: Do not silently select a row at that boundary, transfer an oral table, or extrapolate to another indication.

Evidence for this qualification

Source-specific qualification; independent clinician review pending.

Confirm the product, indication and renal measure. The selected summary is not a complete prescribing monograph.

Choose a source to read (2)

Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

Official source

Pfizer Medical / CYKLOKAPRON prescribing information

Product / population
CYKLOKAPRON intravenous injection for short-term hemorrhage prevention/reduction with tooth extraction in hemophilia; not an obstetric, trauma or oral menstrual-bleeding protocol.
Renal measure
Serum creatinine, mg/dL

Manufacturer-hosted prescribing information; no DailyMed Set ID or SPL archive check performed for this source.

Renal dosing, restrictions and evidence limits

The renal table uses serum creatinine, not CrCl. SCr 1.36-2.83 mg/dL: 10 mg/kg IV twice daily. SCr 2.83-5.66: 10 mg/kg IV daily. Above 5.66: 10 mg/kg IV every 48 hours OR 5 mg/kg IV every 24 hours. The table prints 2.83 in both adjacent bands; this tool does not silently assign that exact boundary.

Reduction applies to doses before and after tooth extraction. Keep the labeled short course (2-8 days after extraction) and actual-body-weight context. IV only: neuraxial administration is contraindicated and can be fatal. No dialysis supplement or other-indication regimen is inferred.

Source revision: 8/2025 | Retrieved: 2026-09-09. Retrieval date is not the revision date.

Source: https://www.pfizermedical.com/cyklokapron

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

Full source card / provenance

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Source-first renal review

Evidence sources and renal implications

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Read 1 source difference / applicability notes

Official product label

Pfizer Medical / CYKLOKAPRON prescribing information

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

CYKLOKAPRON intravenous injection for short-term hemorrhage prevention/reduction with tooth extraction in hemophilia; not an obstetric, trauma or oral menstrual-bleeding protocol.

Renal method: Serum creatinine, mg/dL
Retrieved: 2026-09-09

Read local renal resultOpen original reference
GlobalRPh RX List

GlobalRPh RX List - CYKLOKAPRON

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

CYKLOKAPRON intravenous injection for short-term hemorrhage prevention/reduction with tooth extraction in hemophilia; not an obstetric, trauma or oral menstrual-bleeding protocol.

Renal method: Serum creatinine, mg/dL
Retrieved: 2026-09-09

Read local renal resultOpen original reference

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

Product / population check

Confirm the exact formulation before using a renal source

These links compare product identities, not interchangeable doses. A selected summary is not a complete prescribing monograph.

Source-specific review points

IV-only administration and an overlapping printed boundary

Read the attributed comparison notes and source cards below. No conflict has been silently adjudicated.

Source-quality holds
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Jump to renal guidanceRead 1 difference / caution notesClinician guide

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Build a source-review outline for documentation

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Renal-context checklist: population, kidney trend and dialysis

These prompts are a reading aid, not a prescription checklist or proof that all requirements have been met. No selections are stored or sent to a server.

Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

Read before choosing a regimen

Source differences and product cautions

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These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.

boundary route and indication

IV-only administration and an overlapping printed boundary

The official renal table repeats an exact creatinine value in adjacent rows. Its doses are scoped to the hemophilia/tooth-extraction indication.

How to use this: Do not silently select a row at that boundary, transfer an oral table, or extrapolate to another indication.

GlobalRPh RX List - CYKLOKAPRONPfizer Medical / CYKLOKAPRON prescribing informationTranexamic acid - LYSTEDA oral tablets

Source-specific interpretation; independent clinician adjudication pending.

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Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

Compare or copy source versions

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Original content / product scopePfizer Medical / CYKLOKAPRON prescribing informationGlobalRPh RX List - CYKLOKAPRON
Choose two source checkboxes below.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/cyklokapron-drug/

Exact product and population

CYKLOKAPRON intravenous injection for short-term hemorrhage prevention/reduction with tooth extraction in hemophilia; not an obstetric, trauma or oral menstrual-bleeding protocol.

RDM54-SCOPE-tranexamic-acid-cyklokapron · Source section: Selected source product scopeRenal section finder
Separate U.S. product-label layer

FDA / DailyMed dosing and renal information

Official

Pfizer Medical / CYKLOKAPRON prescribing information

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Pfizer Medical / product prescribing information · CYKLOKAPRON intravenous injection for short-term hemorrhage prevention/reduction with tooth extraction in hemophilia; not an obstetric, trauma or oral menstrual-bleeding protocol.

Renal method: Serum creatinine, mg/dL
Source date: 8/2025
Retrieved: 2026-09-09

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

The renal table uses serum creatinine, not CrCl. SCr 1.36-2.83 mg/dL: 10 mg/kg IV twice daily. SCr 2.83-5.66: 10 mg/kg IV daily. Above 5.66: 10 mg/kg IV every 48 hours OR 5 mg/kg IV every 24 hours. The table prints 2.83 in both adjacent bands; this tool does not silently assign that exact boundary.

Reduction applies to doses before and after tooth extraction. Keep the labeled short course (2-8 days after extraction) and actual-body-weight context. IV only: neuraxial administration is contraindicated and can be fatal. No dialysis supplement or other-indication regimen is inferred.

RDM54-official-tranexamic-acid-cyklokapron-afda5654ab-C1 · Source locator: Boxed Warning; sections 1, 2.1-2.3 Table 1 and 4

Source-specific limits

Manufacturer-hosted prescribing information; no DailyMed Set ID or SPL archive check performed for this source.

Source identity and provenance
Source family
product_label
Source
https://www.pfizermedical.com/cyklokapron
Retrieved
2026-09-09
Exact label title
CYKLOKAPRON (tranexamic acid) injection
Label revision
8/2025
Renal-function method
Serum creatinine, mg/dL
Source date/version
8/2025
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
e15038619fad912b504a4ee3053b208ffbcd694edb82a92e1137943a2bf59a18
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - CYKLOKAPRON

Open original reference

Open / share this exact local source

GlobalRPh-hosted RX List · CYKLOKAPRON intravenous injection for short-term hemorrhage prevention/reduction with tooth extraction in hemophilia; not an obstetric, trauma or oral menstrual-bleeding protocol.

Renal method: Serum creatinine, mg/dL
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-09

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

The renal table uses serum creatinine, not CrCl. SCr 1.36-2.83 mg/dL: 10 mg/kg IV twice daily. SCr 2.83-5.66: 10 mg/kg IV daily. Above 5.66: 10 mg/kg IV every 48 hours OR 5 mg/kg IV every 24 hours. The table prints 2.83 in both adjacent bands; this tool does not silently assign that exact boundary.

Reduction applies to doses before and after tooth extraction. Keep the labeled short course (2-8 days after extraction). IV only; not an oral regimen. No dialysis supplement or other-indication regimen is inferred.

RDM54-rxlist-tranexamic-acid-cyklokapron-cfb066c32a-C1 · Source locator: Dosage and Administration; Renal Impairment; selected Warnings and Precautions

Source-specific limits

Selected sections only. Source mirror and underlying label are not independent confirmations.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/cyklokapron-drug/
Retrieved
2026-09-09
Renal-function method
Serum creatinine, mg/dL
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
123e01d50cafa1c857e2f0094d7aec9874a1e392b515ff461867129ab3f277d0

Provenance and preservation

Additional summaries stored on this page: 1 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/cyklokapron-drug/
Source retrieval
2026-09-09. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
0993f96a8dcb51f6154fecff3d6d37f8c966e6ab1a6614dae2e4874dd09d6e8b
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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