Pregabalin - LYRICA CR extended release | GlobalRPh Renal Dosing Master

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LYRICA CR: formulation limits and the printed clearance-boundary overlap

The selected table overlaps at exactly CrCl 60. It directs use of an immediate-release product below the CR eligibility range and in hemodialysis.

Before applying: Do not silently repair the boundary or substitute CR for IR milligram-for-milligram. Confirm the applicable full product instructions.

Also check: LYRICA CR: formulation limits and the printed clearance-boundary overlap

Rxlist source

GlobalRPh RX List - LYRICA CR

Product / population: Pregabalin - LYRICA CR extended release; selected renal source sections only, not a complete prescribing monograph.
Renal measure: Cockcroft-Gault creatinine clearance (CrCl), mL/min.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

First determine the normal-function daily dose for the indication. The table maps 165/330/495/660 mg daily at CrCl >=60 to 82.5/165/247.5/330 mg daily in the printed CrCl 30-60 band, all once daily. The printed bands overlap at exactly 60; confirm the applicable label rather than silently choosing a row. LYRICA CR is not recommended below CrCl 30 or during hemodialysis; the label directs use of LYRICA instead. Immediate-release and CR milligrams are not interchangeable.

Source revision: RX page prints April 2025. | Retrieved: 2026-09-08. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/lyrica-cr-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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Evidence sources and renal implications

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GlobalRPh RX List

GlobalRPh RX List - LYRICA CR

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Pregabalin - LYRICA CR extended release; selected renal source sections only, not a complete prescribing monograph.

Renal method: Cockcroft-Gault creatinine clearance (CrCl), mL/min.
Retrieved: 2026-09-08

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Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

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Source-specific review points

LYRICA CR: formulation limits and the printed clearance-boundary overlap

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Jump to renal guidance Read 1 difference / caution notes Clinician guide

Only one eligible source version is stored here. No second source is inferred from a reference link. Independent corroboration is still needed.

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Renal-context checklist: population, kidney trend and dialysis

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Population Kidney-function trend Renal replacement setting

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See source-specific renal methods and the clinical interpretation guide for the supporting context.

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Source differences and product cautions

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These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.

boundary units

LYRICA CR: formulation limits and the printed clearance-boundary overlap

The selected table overlaps at exactly CrCl 60. It directs use of an immediate-release product below the CR eligibility range and in hemodialysis.

How to use this: Do not silently repair the boundary or substitute CR for IR milligram-for-milligram. Confirm the applicable full product instructions.

GlobalRPh RX List - LYRICA CR Pregabalin - immediate release

Source-specific interpretation; independent clinician adjudication pending.

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Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

Rxlist source

GlobalRPh RX List - LYRICA CR

Pregabalin - LYRICA CR extended release; selected renal source sections only, not a complete prescribing monograph.

Method: Cockcroft-Gault creatinine clearance (CrCl), mL/min.

Renal dosing, restrictions and evidence limits Read this complete source summary

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

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All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.

Original content / product scope GlobalRPh RX List - LYRICA CR

Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/lyrica-cr-drug/

Exact product and population

Pregabalin - LYRICA CR extended release; selected renal source sections only, not a complete prescribing monograph.

RDM47-SCOPE-pregabalin-lyrica-cr · Source section: Selected source product scopeRenal section finder

Locally imported selected renal sections

GlobalRPh RX List renal information

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GlobalRPh RX List - LYRICA CR

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GlobalRPh-hosted RX List · Pregabalin - LYRICA CR extended release; selected renal source sections only, not a complete prescribing monograph.

Renal method: Cockcroft-Gault creatinine clearance (CrCl), mL/min.
Source date: RX page prints April 2025.
Retrieved: 2026-09-08

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

RDM47-rxlist-pregabalin-lyrica-cr-e55530db19-C1 · Source locator: Dosage: conversion and renal Table 2, lines 52-91.

Source identity and provenance

Source family: product_label_mirror
Source: https://globalrph.com/rx-list/lyrica-cr-drug/
Retrieved: 2026-09-08
Renal-function method: Cockcroft-Gault creatinine clearance (CrCl), mL/min.
Source date/version: RX page prints April 2025.
Hash meaning: SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256: 04a3f7d40434c18581c83c79a846a5f88605fa68d772a4c5bf724f0c1ea05132

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source: https://globalrph.com/rx-list/lyrica-cr-drug/
Source retrieval: 2026-09-08. This is not the source publication or label revision date.
Original source type: rxlist summary
Local text SHA-256: bb35f9b1f9d45f51abcf22d8d92278fb170a5fcc80b4e364f83e1005016d22f8
Import versus clinical validation: Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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