GlobalRPh RX List - ORBACTIV
- Product / population
- Oritavancin - ORBACTIV intravenous infusion; selected source sections only, not a complete prescribing monograph.
- Renal measure
- Creatinine clearance (CrCl), mL/min; equation not established in the selected dosing passage.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
For adult acute bacterial skin and skin structure infection, the ORBACTIV regimen is 1200 mg IV over 3 hours. Mild or moderate renal impairment requires no adjustment; severe impairment has not been evaluated. The PK analysis describes CrCl 50-79 and 30-49 mL/min groups. Oritavancin is not removed by hemodialysis, but no dedicated dialysis studies were conducted. ORBACTIV and KIMYRSA differ in preparation and infusion instructions; use the exact product, not a mixed regimen.