Oritavancin injection (KIMYRSA) | GlobalRPh Renal Dosing Master

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No routine renal adjustment does not remove heparin restrictions

Mild/moderate renal dosing guidance coexists with a 120-hour IV unfractionated-heparin contraindication due to aPTT interference.

Before applying: Reconcile the anticoagulant and monitoring plan with the dialysis team before treatment. A renal dose table alone is insufficient.

Also check: No routine renal adjustment does not remove heparin restrictions

Rxlist source

GlobalRPh RX List - KIMYRSA

Product / population: KIMYRSA IV product; assess dialysis anticoagulants and laboratory interference before use.
Renal measure: Mild/moderate impairment: no adjustment; severe impairment not evaluated.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

No dose adjustment is required for mild or moderate renal impairment; severe impairment has not been evaluated. Hemodialysis does not remove oritavancin. IV unfractionated heparin is contraindicated for 120 hours after KIMYRSA because aPTT can be falsely prolonged. That laboratory/anticoagulant restriction remains relevant even when no renal dose change is required. This is not a substitute dialysis anticoagulation protocol.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/kimyrsa-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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GlobalRPh RX List

GlobalRPh RX List - KIMYRSA

Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

KIMYRSA IV product; assess dialysis anticoagulants and laboratory interference before use.

Renal method: Mild/moderate impairment: no adjustment; severe impairment not evaluated.
Retrieved: 2026-09-07

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monitoring or safety

No routine renal adjustment does not remove heparin restrictions

Mild/moderate renal dosing guidance coexists with a 120-hour IV unfractionated-heparin contraindication due to aPTT interference.

How to use this: Reconcile the anticoagulant and monitoring plan with the dialysis team before treatment. A renal dose table alone is insufficient.

GlobalRPh RX List - KIMYRSA

Source-specific interpretation; independent clinician adjudication pending.

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

Rxlist source

GlobalRPh RX List - KIMYRSA

KIMYRSA IV product; assess dialysis anticoagulants and laboratory interference before use.

Method: Mild/moderate impairment: no adjustment; severe impairment not evaluated.

Renal dosing, restrictions and evidence limits Read this complete source summary

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Original content / product scope GlobalRPh RX List - KIMYRSA

Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/kimyrsa-drug/

Exact product and population

KIMYRSA IV product; assess dialysis anticoagulants and laboratory interference before use.

RDM42-SCOPE-oritavancin-kimyrsa · Source section: Selected source product scopeRenal section finder

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GlobalRPh RX List renal information

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GlobalRPh RX List - KIMYRSA

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GlobalRPh-hosted RX List · KIMYRSA IV product; assess dialysis anticoagulants and laboratory interference before use.

Renal method: Mild/moderate impairment: no adjustment; severe impairment not evaluated.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.

Qualified no-adjustment statement. Apply only to the population, product and renal range described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

RDM42-rxlist-oritavancin-kimyrsa-70407ee5d8-C1 · Source locator: Renal impairment; Contraindications / IV unfractionated heparin

Source identity and provenance

Source family: product_label_mirror
Source: https://globalrph.com/rx-list/kimyrsa-drug/
Retrieved: 2026-09-07
Renal-function method: Mild/moderate impairment: no adjustment; severe impairment not evaluated.
Source date/version: Source revision date not established in selected retrieval.
Hash meaning: SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256: 6465e6bdb5757f9ece7eda90d834060f26de2b09d618080c8b1e691f6e7b4535

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source: https://globalrph.com/rx-list/kimyrsa-drug/
Source retrieval: 2026-09-07. This is not the source publication or label revision date.
Original source type: rxlist summary
Local text SHA-256: c1687dc1b8cdb54ecdf5793332bf6e8299021a112e072006601f4bc58fe75d40
Import versus clinical validation: Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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