GlobalRPh RX List - KAPVAY
- Product / population
- Oral clonidine ER; renal initiation and monitoring, including pediatric evidence limitation.
- Renal measure
- Degree of renal impairment; no numeric cutoff supplied.
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
Base the initial dose on the degree of renal impairment, monitor carefully and titrate according to response. Watch for hypotension and bradycardia. The source says routine hemodialysis removes little clonidine and no supplemental post-dialysis dose is required. Pediatric renal pharmacokinetics were not assessed; no numeric pediatric renal starting dose is established here.