GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Amoxicillin / clavulanate - AUGMENTIN XR extended-release tablets

AUGMENTIN XR

READ THE SOURCE-SPECIFIC ANSWER

Renal guidance at a glance

Cautions / source differences (1)
Review first - source-specific qualification

XR renal restriction; current-label confirmation open

The selected XR mirror contraindicates CrCl below 30 and hemodialysis. Its restriction is not the conventional AUGMENTIN reduced-dose table.

Before applying: Verify current exact-product labeling; no XR renal dose is inferred.

Evidence for this qualification

Source-specific interpretation; independent clinician adjudication pending.

Confirm the product, indication and renal measure. The selected summary is not a complete prescribing monograph.

Choose a source to read (1)

Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

Rxlist source

GlobalRPh RX List - AUGMENTIN XR

Product / population
AUGMENTIN XR extended-release amoxicillin/clavulanate tablets only.
Renal measure
Source-specific renal measure; see text

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Before using this finding

A restriction is not a reduced-dose instruction. Do not replace with conventional tablets by amoxicillin amount alone.

Current exact-product official label was not retrieved in this release. This is a dated mirror-source restriction, not an independently approved protocol.

No new official-label card was obtained for this product in v6.1. Earlier source layers, if present, were retained but not rechecked.

Renal guidance and important limits

The RX mirror states that AUGMENTIN XR is contraindicated with creatinine clearance below 30 mL/min and in hemodialysis patients. Renal-impairment pharmacokinetics have not been studied for this extended-release product. The conventional AUGMENTIN reduced-dose table must not be applied to XR. Renal restriction is additional to the product's serious beta-lactam hypersensitivity and prior amoxicillin/clavulanate-associated cholestatic jaundice/hepatic dysfunction contraindications.

Source revision: Revision not established in selected retrieval | Retrieved: 2026-09-10. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/augmentin-xr-drug/

Scope: Selected source sections stored locally. Not a complete monograph or independent clinical approval. GlobalRPh v6.6.

Full source card / provenance

All sources, comparison tools and evidence navigation
Source-specific interpretation

What the dialysis evidence actually supports

Removal information alone does not define a maintenance dose, supplemental dose or dialysis schedule. A reported regimen still requires its product, indication, renal measure and dialysis assumptions to match the patient.

GlobalRPh RX List - AUGMENTIN XR

Authored v6.1; retrieved 2026-09-10 - retained source, not freshly reviewed in this release

No dialysis regimen established in selected content

Read the source and its limits

These manual classifications apply only to the identified selected sections, not every retained source or the entire prescribing information. They are not dosing clearance.

Source-first renal review

Evidence sources and renal implications

Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.

Read 1 source difference / applicability notes

GlobalRPh RX List

GlobalRPh RX List - AUGMENTIN XR

Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.
Before using this finding

A restriction is not a reduced-dose instruction. Do not replace with conventional tablets by amoxicillin amount alone.

Dialysis evidence: No dialysis regimen established in selected content

AUGMENTIN XR extended-release amoxicillin/clavulanate tablets only.

Renal method: Source-specific renal measure; see text
Retrieved: 2026-09-10

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

Product / population check

Confirm the exact formulation before using a renal source

These links compare product identities, not interchangeable doses. A selected summary is not a complete prescribing monograph.

Source-quality holds
Find text within this drug
Find a term without leaving this drug

Search the stored clinical text

Locate a word or phrase within this drug's source summaries. Choose all sources or one source to focus the search. The selection never hides warnings or source text, changes a dose, or proves that a renal finding is absent.

Find:

Enter at least two characters. Searches stay on this page and are not saved or sent.

All source summaries, original wording and provenance
Before applying a renal protocol

Check the setting. Compare whole sources.

No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.

Share a reproducible source review

Choose sources below, then open a print-ready comparison with product scope, renal method, dates and cautions. Links can pin the exact local cards; they never contain patient values or choose a dose.

Open / share selected sources

Only one eligible source version is stored here. No second source is inferred from a reference link. Independent corroboration is still needed.

Build a source-review outline for documentation

This creates a blank decision outline with the source identities you select, not a dose recommendation or completed clinical assessment. No patient fields are collected, saved or sent. Complete the clinical decisions in your approved documentation system.

Choose one or two sources above or use the source checkboxes below.

Renal-context checklist: population, kidney trend and dialysis

These prompts are a reading aid, not a prescription checklist or proof that all requirements have been met. No selections are stored or sent to a server.

Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

Read before choosing a regimen

Source differences and product cautions

Search differences across all drugs

These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.

Go directly to the relevant source section

Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

Compare or copy source versions

All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.

Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/augmentin-xr-drug/

Exact product and population

AUGMENTIN XR extended-release amoxicillin/clavulanate tablets only.

RDM61-SCOPE-amoxicillin-clavulanate-augmentin-xr · Source section: Selected source product scopeRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - AUGMENTIN XR

Open original reference

Open / share this exact local source

GlobalRPh-hosted RX List · AUGMENTIN XR extended-release amoxicillin/clavulanate tablets only.

Renal method: Source-specific renal measure; see text
Source date: Revision not established in selected retrieval
Retrieved: 2026-09-10

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Restriction or avoidance guidance. Read the specific threshold, age, formulation and dialysis exclusions; do not generalize across products.
Before using this finding

A restriction is not a reduced-dose instruction. Do not replace with conventional tablets by amoxicillin amount alone.

Dialysis evidence: No dialysis regimen established in selected content

Selected source sections stored locally. Not a complete monograph or independent clinical approval.

Renal guidance and important limits

The RX mirror states that AUGMENTIN XR is contraindicated with creatinine clearance below 30 mL/min and in hemodialysis patients. Renal-impairment pharmacokinetics have not been studied for this extended-release product. The conventional AUGMENTIN reduced-dose table must not be applied to XR. Renal restriction is additional to the product's serious beta-lactam hypersensitivity and prior amoxicillin/clavulanate-associated cholestatic jaundice/hepatic dysfunction contraindications.

RDM61-rxlist-amoxicillin-clavulanate-augmentin-xr-09a588dabe-C1 · Source locator: Dosage and Administration: renal impairment; named precautions

Source-specific limits

Current exact-product official label was not retrieved in this release. This is a dated mirror-source restriction, not an independently approved protocol.

No new official-label card was obtained for this product in v6.1. Earlier source layers, if present, were retained but not rechecked.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/augmentin-xr-drug/
Retrieved
2026-09-10
Renal-function method
Source-specific renal measure; see text
Source date/version
Revision not established in selected retrieval
Hash meaning
Local authored summary, not source HTML/XML/PDF bytes
Local summary SHA-256
275b77a5e9861229c588a8a8ca671b3621bf87234baaf339b796db074668a0bf

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/augmentin-xr-drug/
Source retrieval
2026-09-10. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
fc198b9033779ccfe65c403aa1f66bd50a79d73be123436d2ef76f135d77aff6
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

Read the full coverage report