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GlobalRPh Renal Dosing Master v6.6

Clinical interpretation | Version 6.6

Find the difference.
Keep the context.

Search documented disagreements and product cautions across the local library. Compare complete source versions on the drug page before choosing a regimen.

Search source differences

445 notes across 406 drug/product records.

How to interpret these notes

Generic name, brand, source or issueType of differenceAdded in v6.6

Clear filters Export all filtered notes

Search medication names and documented issues only. Do not enter patient information. This directory submits search filters to the server; the within-drug text finder remains a separate local feature.

A difference is not always a contradiction

Compare indication, formulation, route, population, renal method, dialysis conditions and source date. A safety update or source-quality failure is not an alternative dose. These notes are not independent clinical approval, and sources are not ranked or averaged.

445 matching notes. Showing 17-32; page 2 of 28.

source scope and renal guidance

Amantadine (source heading: Amantidine)

Before use: Amantadine (source heading: Amantidine)

The retrieved SYMMETREL mirror uses 100 mg every 7 days below 15, while the US IR capsule label uses 200 mg every 7 days. Other interval bands and first-dose instructions also differ; mirror jurisdiction/applicability is unreconciled.

What to reconcile

Treat the SYMMETREL mirror as a source-quality hold. Do not apply its schedule to the US IR capsule or an extended-release product.

2 source identities and dates

Amantadine immediate-release capsules - Alembic US label

DailyMed / NLM exact product labeling | Source revision: 06/2025
Immediate-release 100 mg capsules; adult renal instructions. Not GOCOVRI or OSMOLEX ER.

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GlobalRPh RX List - SYMMETREL

GlobalRPh-hosted RX List | Source revision: April 2019 (printed Novartis mirror revision)
Historical SYMMETREL mirror; jurisdiction and exact marketed-product applicability unresolved.

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Source-specific interpretation; independent clinician adjudication pending. Added: v6.4.

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boundary units

Amantadine - OSMOLEX ER tablets

OSMOLEX ER: change dosing frequency and titration interval, not a daily fraction

The table uses MDRD indexed eGFR; other passages call the measure indexed CrCl. Reduced-frequency bands must not be converted into daily administration.

What to reconcile

Keep the two intervals distinct and reconcile source terminology; do not substitute a GOCOVRI schedule.

1 source identities and dates

GlobalRPh RX List - OSMOLEX ER

GlobalRPh-hosted RX List | Source revision: Source revision date not established in selected retrieval.
Amantadine - OSMOLEX ER tablets; selected source sections only, not a complete prescribing monograph.

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Source-specific interpretation; independent clinician adjudication pending. Added: v4.9.

Open / share source review Open drug and compare sources Amantadine (source heading: Amantidine) - related, not interchangeable GOCOVRI extended-release capsules: February 2026 label - related, not interchangeable

formulation and monitoring

Amikacin liposome inhalation suspension - ARIKAYCE

Inhaled liposomal exposure does not authorize an IV schedule

Low systemic exposure supports a qualified accumulation statement, but renal impairment was not studied and monitoring remains advised.

What to reconcile

Keep ARIKAYCE distinct from injectable amikacin; do not transplant aminoglycoside intervals or dialysis replacement doses.

1 source identities and dates

GlobalRPh RX List - ARIKAYCE

GlobalRPh-hosted RX List | Source revision: Source revision date not established in selected retrieval.
ARIKAYCE inhalation suspension for the labeled MAC lung-disease setting in combination treatment; not injectable amikacin sulfate.

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Source-specific interpretation; independent clinician adjudication pending. Added: v5.5.

Open / share source review Open drug and compare sources Amikacin - related, not interchangeable

single dose and monitoring

Amisulpride - BARHEMSYS intravenous injection

Single-dose renal PK is not repeated-dose safety

The selected IV PONV studies excluded dialysis; the label does not supply a dialysis protocol.

What to reconcile

Keep QT and electrolyte precautions visible. Do not transfer oral psychiatric schedules.

2 source identities and dates

GlobalRPh RX List - BARHEMSYS

GlobalRPh-hosted RX List | Source revision: Source revision date not established in selected retrieval.
Single-dose IV BARHEMSYS for adult postoperative nausea/vomiting; not repeated oral psychiatric treatment.

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DailyMed / BARHEMSYS exact product label

DailyMed / Acacia Pharma Ltd | Source revision: 9/2022
Single-dose IV BARHEMSYS for adult postoperative nausea/vomiting; not repeated oral psychiatric treatment.

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Source-specific interpretation; independent clinician adjudication pending. Added: v5.6.

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source scope and renal guidance

Amoxicillin

Age and weight remain part of the renal table

The renal heading covers adults and children aged at least 3 months weighing more than 40 kg; it is not a small-child or neonatal schedule. The source also specifies additional doses both during and at the end of hemodialysis.

What to reconcile

Confirm population and local dialysis protocol. Do not silently change the source schedule.

1 source identities and dates

GlobalRPh RX List - AMOXIL

GlobalRPh-hosted RX List | Source revision: Revision not established in selected retrieval
AMOXIL oral capsules/tablets/suspension; selected severe-renal paragraph. Not a small-child or neonatal renal dosing table.

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Source-specific interpretation; independent clinician adjudication pending. Added: v6.1.

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source scope and renal guidance

Amoxicillin

Before use: Amoxicillin

Galway uses indexed eGFR and inpatient IV/PO ranges, whereas UCSF provides indication-specific oral CrCl schedules and specified dialysis assumptions. The printed UCSF headings leave exactly 30 unassigned. These protocols are not interchangeable.

What to reconcile

Resolve the printed boundary and match the indication, oral route and actual dialysis prescription.

2 source identities and dates

Galway GAPP - amoxicillin IV/PO

Galway University Hospitals - GAPP | Source revision: Revision not established in selected retrieval
Hospitalized adults; Irish institutional guidance, not a US product label.

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UCSF - amoxicillin oral renal and dialysis tables

UCSF Infectious Diseases Management Program | Source revision: Revision not established in selected retrieval
Adults; oral dosing for selected indications.

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Source-specific interpretation; independent clinician adjudication pending. Added: v6.4.

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source scope and renal guidance

Amoxicillin / clavulanate - AUGMENTIN ES-600 oral suspension

No pediatric renal ladder imported

ES-600 is a distinct pediatric suspension. The selected dosing section supplies no renal table; removal in overdose does not establish a maintenance dose.

What to reconcile

Do not substitute adult conventional/XR instructions or infer no adjustment.

1 source identities and dates

GlobalRPh RX List - AUGMENTIN ES-600

GlobalRPh-hosted RX List | Source revision: Revision not established in selected retrieval
AUGMENTIN ES-600 pediatric suspension, 600 mg amoxicillin per 5 mL. Not conventional or XR AUGMENTIN.

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Source-specific interpretation; independent clinician adjudication pending. Added: v6.1.

Open / share source review Open drug and compare sources Amoxicillin/Clav - related, not interchangeable Amoxicillin / clavulanate - AUGMENTIN XR extended-release tablets - related, not interchangeable

source scope and renal guidance

Amoxicillin / clavulanate - AUGMENTIN XR extended-release tablets

XR renal restriction; current-label confirmation open

The selected XR mirror contraindicates CrCl below 30 and hemodialysis. Its restriction is not the conventional AUGMENTIN reduced-dose table.

What to reconcile

Verify current exact-product labeling; no XR renal dose is inferred.

1 source identities and dates

GlobalRPh RX List - AUGMENTIN XR

GlobalRPh-hosted RX List | Source revision: Revision not established in selected retrieval
AUGMENTIN XR extended-release amoxicillin/clavulanate tablets only.

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Source-specific interpretation; independent clinician adjudication pending. Added: v6.1.

Open / share source review Open drug and compare sources Amoxicillin/Clav - related, not interchangeable Amoxicillin / clavulanate - AUGMENTIN ES-600 oral suspension - related, not interchangeable

source scope and renal guidance

Amoxicillin/Clav

Conventional AUGMENTIN is not XR or ES-600

The conventional renal table cannot be transferred to XR, and clavulanate content differs among formulations.

What to reconcile

Match both component strengths and formulation before using any table.

1 source identities and dates

GlobalRPh RX List - AUGMENTIN

GlobalRPh-hosted RX List | Source revision: Revision not established in selected retrieval
Conventional AUGMENTIN adult renal paragraph; not extended-release or ES-600.

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Source-specific interpretation; independent clinician adjudication pending. Added: v6.1.

Open / share source review Open drug and compare sources Amoxicillin / clavulanate - AUGMENTIN XR extended-release tablets - related, not interchangeable Amoxicillin / clavulanate - AUGMENTIN ES-600 oral suspension - related, not interchangeable

specialist indication regimen

Ampicillin/Sulbactam

High-dose CRAB treatment is not the routine label regimen

The ID-directed UCSF CRAB regimen can exceed the routine labeled sulbactam exposure. It has different infusion duration and renal eligibility, and its printed extended-infusion columns leave exactly 60 unassigned.

What to reconcile

Use infectious-disease/antimicrobial-stewardship oversight and the exact infection context. Do not extrapolate this row into unlisted renal or dialysis settings. Keep total combination grams distinct from sulbactam grams.

2 source identities and dates

GlobalRPh RX List - Unasyn

GlobalRPh-hosted RX List | Source revision: Source revision date not established in selected retrieval.
Adults; IV/IM ampicillin plus sulbactam in the 2:1 ratio. Total-combination grams.

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UCSF: ampicillin/sulbactam adult institutional dosing

UCSF Infectious Diseases Management Program | Source revision: Source revision date not established in selected retrieval.
Adult institutional antimicrobial dosing; standard and separately ID-directed CRAB pathways.

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Source-specific interpretation; independent clinician adjudication pending. Added: v3.6.

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renal metric and threshold

Ampicillin/Sulbactam

UNASYN label and UCSF do not use identical renal bands

At the printed value 30, the RX label table places patients in its at-least-30 row, whereas UCSF standard dosing places 30 in its 15-30 row. The RX heading also prints indexed clearance while UCSF uses mL/min.

What to reconcile

Reconcile the renal metric and endpoint before selecting an interval. Do not choose whichever row is more convenient or merge the label dose range with an institutional interval.

2 source identities and dates

GlobalRPh RX List - Unasyn

GlobalRPh-hosted RX List | Source revision: Source revision date not established in selected retrieval.
Adults; IV/IM ampicillin plus sulbactam in the 2:1 ratio. Total-combination grams.

Read this stored source

UCSF: ampicillin/sulbactam adult institutional dosing

UCSF Infectious Diseases Management Program | Source revision: Source revision date not established in selected retrieval.
Adult institutional antimicrobial dosing; standard and separately ID-directed CRAB pathways.

Read this stored source

Source-specific interpretation; independent clinician adjudication pending. Added: v3.6.

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population or indication

Anakinra (KINERET)

Renal interval change does not substitute the adult RA dose

The official label considers alternate-day administration of the prescribed dose below CrCl 30. The adult RA 100 mg dose is not the weight-based NOMID/DIRA dose.

What to reconcile

Retain indication and population when changing the interval. The separate official retrieval does not repair the failed RX page attempt.

1 source identities and dates

KINERET - official renal dosing and indication distinction

DailyMed / Swedish Orphan Biovitrum | Source revision: October 2025
Subcutaneous anakinra: RA versus NOMID/DIRA doses remain distinct.

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Source-specific interpretation; independent clinician adjudication pending. Added: v4.2.

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dose table scope

Apomorphine - ONAPGO continuous subcutaneous infusion

ONAPGO: initial extra dose differs from continuous and later doses

The May 2026 official renal instruction specifically limits the initial extra dose. The older RX rendering supplies PK information without that usable prescribing subsection.

What to reconcile

Use the complete official product instructions; do not lower every dose automatically or substitute intermittent apomorphine.

2 source identities and dates

GlobalRPh RX List - ONAPGO

GlobalRPh-hosted RX List | Source revision: RX page prints February 2025.
Apomorphine - ONAPGO continuous subcutaneous infusion; selected source sections only, not a complete prescribing monograph.

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ONAPGO - official renal prescribing summary

DailyMed / MDD US Operations, LLC | Source revision: Prescribing information revised May 2026; IFU separately revised June 2026.
ONAPGO 98 mg/20 mL (4.9 mg/mL) solution for continuous subcutaneous infusion in adults with advanced Parkinson disease; not an intermittent apomorphine product. Selected renal sections, not a complete pump prescription.

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Source-specific interpretation; independent clinician adjudication pending. Added: v4.9.

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monitoring scope

Arimoclomol - MIPLYFFA

MIPLYFFA: creatinine change may not equal a fall in GFR

The current label describes a creatinine change not attributable to glomerular function and recommends alternative kidney assessments. Its selected eGFR units omit an indexing denominator.

What to reconcile

Do not dismiss possible AKI. Review BUN, cystatin C or measured GFR in clinical context; do not silently convert the printed renal bands.

2 source identities and dates

GlobalRPh RX List - MIPLYFFA

GlobalRPh-hosted RX List | Source revision: Source revision date not established in selected retrieval.
Arimoclomol - MIPLYFFA; selected renal source sections only, not a complete prescribing monograph.

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Arimoclomol - MIPLYFFA official label

DailyMed / Acer Therapeutics Inc | Source revision: Prescribing information revised 3/2026.
Arimoclomol - MIPLYFFA official label; selected renal source sections only, not a complete prescribing monograph.

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Source-specific interpretation; independent clinician adjudication pending. Added: v4.7.

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indication scope

Atovaquone / proguanil - MALARONE

MALARONE: prevention contraindication versus qualified treatment use

The selected source distinguishes prophylaxis from short-course treatment in severe renal impairment. Its older revision also requires a currency check.

What to reconcile

Match prevention versus treatment and both active ingredients; do not apply atovaquone-alone instructions.

1 source identities and dates

GlobalRPh RX List - MALARONE

GlobalRPh-hosted RX List | Source revision: RX page prints February 2013; current-label reconciliation remains pending.
Atovaquone / proguanil - MALARONE; selected renal source sections only, not a complete prescribing monograph.

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Source-specific interpretation; independent clinician adjudication pending. Added: v4.7.

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evidence limit

Axatilimab-csfr - NIKTIMVO injection

NIKTIMVO: unchanged exposure is not a renal prescription

The selected population PK range stops before severe impairment. It does not provide a severe-impairment or dialysis regimen.

What to reconcile

Do not convert PK similarity into universal no-adjustment instructions.

1 source identities and dates

GlobalRPh RX List - NIKTIMVO

GlobalRPh-hosted RX List | Source revision: Source revision date not established in selected retrieval.
Axatilimab-csfr - NIKTIMVO injection; selected source sections, not a full prescribing monograph.

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Source-specific interpretation; independent clinician adjudication pending. Added: v4.8.

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What is not established by this directory

Only documented issues are searchable here. Absence of a note is not agreement. A label mirror and the original label are not independent corroboration, and a source's retrieval date is not its revision date.

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