Sofosbuvir / velpatasvir / voxilaprevir - VOSEVI tablets

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Fixed-combination renal permission does not remove other eligibility limits

The VOSEVI renal statement belongs to its three-drug combination, with separate hepatic and prior-treatment limitations.

Before applying: Do not transfer it to every sofosbuvir product or disregard the combination-specific treatment criteria.

Also check: Fixed-combination renal permission does not remove other eligibility limits

Rxlist source

GlobalRPh RX List - VOSEVI

Product / population: Sofosbuvir / velpatasvir / voxilaprevir - VOSEVI tablets; selected renal passages, not a complete prescribing monograph.
Renal measure: Qualitative renal finding; no numerical adjustment threshold inferred.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

The VOSEVI mirror recommends no dosage adjustment for any degree of renal impairment, including dialysis. This does not remove its separate restriction against use in moderate/severe hepatic impairment (Child-Pugh B or C). Regimen eligibility depends on prior HCV treatment and cirrhosis status. Do not apply the single-agent SOVALDI severe-renal limitation to this fixed combination, or use its renal permission as authorization for every sofosbuvir regimen.

Source revision: Mirror prints November 2019. | Retrieved: 2026-09-09. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/vosevi-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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GlobalRPh RX List

GlobalRPh RX List - VOSEVI

No adjustment within stated limits. This does not establish dosing outside the studied renal range or population.

Sofosbuvir / velpatasvir / voxilaprevir - VOSEVI tablets; selected renal passages, not a complete prescribing monograph.

Renal method: Qualitative renal finding; no numerical adjustment threshold inferred.
Retrieved: 2026-09-09

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Source-specific review points

Fixed-combination renal permission does not remove other eligibility limits

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Source differences and product cautions

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scope and applicability

Fixed-combination renal permission does not remove other eligibility limits

The VOSEVI renal statement belongs to its three-drug combination, with separate hepatic and prior-treatment limitations.

How to use this: Do not transfer it to every sofosbuvir product or disregard the combination-specific treatment criteria.

GlobalRPh RX List - VOSEVI Sofosbuvir - SOVALDI in combination antiviral treatment

Source-specific interpretation; independent clinician adjudication pending.

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Renal dosing and precautions

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New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

Rxlist source

GlobalRPh RX List - VOSEVI

Sofosbuvir / velpatasvir / voxilaprevir - VOSEVI tablets; selected renal passages, not a complete prescribing monograph.

Method: Qualitative renal finding; no numerical adjustment threshold inferred.

Renal dosing, restrictions and evidence limits Read this complete source summary

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

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Original content / product scope GlobalRPh RX List - VOSEVI

Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/vosevi-drug/

Exact product and population

Sofosbuvir / velpatasvir / voxilaprevir - VOSEVI tablets; selected renal passages, not a complete prescribing monograph.

RDM53-SCOPE-sofosbuvir-velpatasvir-voxilaprevir-vosevi · Source section: Selected source product scopeRenal section finder

Locally imported selected renal sections

GlobalRPh RX List renal information

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GlobalRPh RX List - VOSEVI

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GlobalRPh-hosted RX List · Sofosbuvir / velpatasvir / voxilaprevir - VOSEVI tablets; selected renal passages, not a complete prescribing monograph.

Renal method: Qualitative renal finding; no numerical adjustment threshold inferred.
Source date: Mirror prints November 2019.
Retrieved: 2026-09-09

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.

No adjustment within stated limits. This does not establish dosing outside the studied renal range or population.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

RDM53-rxlist-sofosbuvir-velpatasvir-voxilaprevir-vosevi-cbe700fa4d-C1 · Source locator: Dosage: renal impairment; moderate/severe hepatic impairment; recommended treatment population.

Source identity and provenance

Source family: product_label_mirror
Source: https://globalrph.com/rx-list/vosevi-drug/
Retrieved: 2026-09-09
Renal-function method: Qualitative renal finding; no numerical adjustment threshold inferred.
Source date/version: Mirror prints November 2019.
Hash meaning: SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256: dab343da4055f568d0e6018a69fe80f9d98f7c18f2022d8e6f97391b874c727f

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source: https://globalrph.com/rx-list/vosevi-drug/
Source retrieval: 2026-09-09. This is not the source publication or label revision date.
Original source type: rxlist summary
Local text SHA-256: a2aee1f24a643a987df8c8dbe23aa8f76c1c40cf993c0edeb64b6f768c625980
Import versus clinical validation: Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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