Ropinirole - extended-release tablets
- Product / population
- Ropinirole - extended-release tablets; selected renal passages, not a complete prescribing monograph.
- Renal measure
- Creatinine clearance (CrCl), mL/min; equation not specified in the selected passage.
The RX REQUIP XL destination failed retrieval in this R pass. This official supplement is not counted as recovered RX content.
Renal dosing, restrictions and evidence limits
For Parkinson disease, CrCl 30-50 mL/min needs no adjustment. With regular hemodialysis, start extended-release ropinirole at 2 mg once daily and titrate to response and tolerability; maximum 18 mg/day. No supplemental postdialysis dose is required. Severe impairment below 30 without regular dialysis has not been studied. These once-daily tablets are not the immediate-release RLS regimen. Do not transfer the IR starting frequency or treat an ER tablet as interchangeable without the label-specific conversion instructions.
Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=307411be-1c4e-44f7-b94d-737a3384c107