Risperidone ER subcutaneous (UZEDY) | GlobalRPh Renal Dosing Master

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Renal instructions require oral titration before this specific depot

UZEDY renal instructions use an oral-risperidone tolerability/titration step followed by a specific monthly subcutaneous regimen. They are not a generic conversion for all risperidone injections.

Before applying: Verify product, route, titration and interaction history. Do not transfer this schedule to IM or every-two-month formulations.

Also check: Renal instructions require oral titration before this specific depot

Rxlist source

GlobalRPh RX List - Uzedy

Product / population: UZEDY extended-release SUBCUTANEOUS injection after oral titration; not IM risperidone.
Renal measure: Renal impairment, not numerically stratified

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

Before UZEDY in renal impairment, titrate oral risperidone to at least 2 mg once daily. Based on response and tolerability after that titration, the recommended UZEDY regimen is 50 mg once monthly. UZEDY itself was not studied in renal impairment; the supporting oral-risperidone data show reduced combined clearance of risperidone and 9-hydroxyrisperidone. The source provides no numeric renal cutoff or dialysis-specific regimen. Do not substitute an every-two-month schedule, another long-acting formulation, or a different injection route. CYP2D6 inhibitors and CYP3A4 inducers need separate review.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/uzedy-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

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GlobalRPh RX List

GlobalRPh RX List - Uzedy

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

UZEDY extended-release SUBCUTANEOUS injection after oral titration; not IM risperidone.

Renal method: Renal impairment, not numerically stratified
Retrieved: 2026-09-07

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formulation and sequence

Renal instructions require oral titration before this specific depot

UZEDY renal instructions use an oral-risperidone tolerability/titration step followed by a specific monthly subcutaneous regimen. They are not a generic conversion for all risperidone injections.

How to use this: Verify product, route, titration and interaction history. Do not transfer this schedule to IM or every-two-month formulations.

GlobalRPh RX List - Uzedy

Source-specific interpretation; independent clinician adjudication pending.

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Renal dosing and precautions

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Rxlist source

GlobalRPh RX List - Uzedy

UZEDY extended-release SUBCUTANEOUS injection after oral titration; not IM risperidone.

Method: Renal impairment, not numerically stratified

Renal dosing, restrictions and evidence limits Read this complete source summary

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Original content / product scope GlobalRPh RX List - Uzedy

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Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/uzedy-drug/

Exact product and population

UZEDY extended-release SUBCUTANEOUS injection after oral titration; not IM risperidone.

RDM36-SCOPE-risperidone-uzedy · Source section: Selected source product scopeRenal section finder

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GlobalRPh RX List - Uzedy

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GlobalRPh-hosted RX List · UZEDY extended-release SUBCUTANEOUS injection after oral titration; not IM risperidone.

Renal method: Renal impairment, not numerically stratified
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

RDM36-rxlist-risperidone-uzedy-ccaef86a57-C1 · Source locator: Dosage modifications; sections on renal impairment and pharmacokinetics.

Source identity and provenance

Source family: product_label_mirror
Source: https://globalrph.com/rx-list/uzedy-drug/
Retrieved: 2026-09-07
Renal-function method: Renal impairment, not numerically stratified
Source date/version: Source revision date not established in selected retrieval.
Hash meaning: SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256: 3584656b94ed954a8a2d030df819b851308aa0edd098e945c953f1f5b7ffb398

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source: https://globalrph.com/rx-list/uzedy-drug/
Source retrieval: 2026-09-07. This is not the source publication or label revision date.
Original source type: rxlist summary
Local text SHA-256: ffbc9b15a008f329c35c4b1fd8fa83a0e195960756e4060f60f2d08abd396820
Import versus clinical validation: Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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