Original GlobalRPh source
- Product / population
- Preserved GlobalRPh source, not a freshly verified product label
- Renal measure
- Use the method specified in the original source
Historical source: not automatically current. Review current official labeling and separately attributed additions before use.
Preserved historical formulations and dosing. This import does not establish current U.S. availability of the listed formulations.
Usual Dosing (Adults)
300 mg orally at bedtime or 150 mg twice daily; maintenance 150 mg at bedtime. Erosive esophagitis: 150 mg orally every 6 hours. IV/IM: 50 mg every 6-8 hours. Continuous IV infusion: 6.25 mg/hour; the source notes higher doses are possible.
Renal Dosing
CrCl above 50 mL/min: no change. 0-49: 150 mg orally every 24 hours or 50 mg IV every 18-24 hours; if needed, dosing may be made every 12 hours with careful monitoring. Exactly 50 is not assigned in the source.
Hemodialysis
150 mg orally every 24 hours or 50 mg IV every 18-24 hours, scheduled after dialysis on dialysis days.