Use the renal measure and units named by this source. Confirm product, indication, age, stable versus changing kidney function, and exact dialysis modality. The selected summary is not a complete prescribing monograph. Renal method and dosing checklist
Choose a source to read (4)
Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.
3 additional source qualifications - review before use
ER use is not recommended below 30 mL/min or on hemodialysis. Confirm the release form before prescribing.
Before applying: Verify the current prescribing information for this presentation.
Also check: URL name does not establish immediate-release formulation; MIRAPEX URL: retrieved body identifies extended release; Mirapex ER - product and source limitations
Official source
Mirapex ER - labeled renal guidance
Renal action and limits
Pramipexole (Mirapex ER), adult once-daily extended-release tablets Creatinine clearance (CrCl), mL/min; use the product-specific calculation
This summary uses the identified dated label. Verify the current label for this presentation before applying the regimen.
Action or finding
At CrCl 30-50 mL/min, start with 0.375 mg every other day. After one week, consider daily dosing according to response and tolerance. Further increases are by 0.375 mg at intervals of at least one week, up to 2.25 mg/day.
Limits and monitoring
ER use is not recommended below 30 mL/min or on hemodialysis. Confirm the release form before prescribing.
Before use
Verify the current prescribing information for this presentation.
Creatinine clearance (CrCl), mL/min; use the product-specific calculation
Source revision
Prescribing information revised 6/2024
Retrieved
2026-11-07 (not the revision date)
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Renal guidance: 2, renal impairment
At CrCl 30-50 mL/min, start with 0.375 mg every other day. After one week, consider daily dosing according to response and tolerance. Further increases are by 0.375 mg at intervals of at least one week, up to 2.25 mg/day. ER use is not recommended below 30 mL/min or on hemodialysis. Confirm the release form before prescribing.
Source revision: Prescribing information revised 6/2024 | Retrieved: 2026-11-07. Retrieval date is not the revision date.
All sources, comparison tools and evidence navigation
Source-specific interpretation
What the dialysis evidence actually supports
Removal information alone does not define a maintenance dose, supplemental dose or dialysis schedule. A reported regimen still requires its product, indication, renal measure and dialysis assumptions to match the patient.
Mirapex ER - labeled renal guidance
Source retrieved 2026-11-07 - confirm current applicability
Use is not recommended / excluded in the named dialysis population; not a dialysis dose
These manual classifications apply only to the identified selected sections, not every retained source or the entire prescribing information. They are not dosing clearance.
Source-first renal review
Evidence sources and renal implications
Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.
Locate a word or phrase within this drug's source summaries. Choose all sources or one source to focus the search. The selection never hides warnings or source text, changes a dose, or proves that a renal finding is absent.
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All source summaries, original wording and provenance
Before applying a renal protocol
Check the setting. Compare whole sources.
No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.
Share a reproducible source review
Choose sources below, then open a print-ready comparison with product scope, renal method, dates and cautions. Links can pin the exact local cards; they never contain patient values or choose a dose.
Select two distinct source versions. The complete stored summaries will appear below.
Source-by-source comparison
These protocols may disagree and may apply to different settings. This view does not reconcile or endorse a patient-specific regimen.
Build a source-review outline for documentation
This creates a blank decision outline with the source identities you select, not a dose recommendation or completed clinical assessment. No patient fields are collected, saved or sent. Complete the clinical decisions in your approved documentation system.
Choose one or two sources above or use the source checkboxes below.
Renal-context checklist: population, kidney trend and dialysis
These prompts are a reading aid, not a prescription checklist or proof that all requirements have been met. No selections are stored or sent to a server.
Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.
These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.
formulation
URL name does not establish immediate-release formulation
The /mirapex-drug/ page body reviewed for this import describes MIRAPEX ER.
How to use this: Use this entry only for the extended-release product; do not transfer its renal schedule to immediate-release pramipexole.
Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.
Independent clinical review is pending. These selected summaries are not an approved institutional dosing protocol. Confirm the exact product, the complete current source and local policy before use.
No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.
Compare or copy source versions
All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
At CrCl 30-50 mL/min, start with 0.375 mg every other day. After one week, consider daily dosing according to response and tolerance. Further increases are by 0.375 mg at intervals of at least one week, up to 2.25 mg/day. ER use is not recommended below 30 mL/min or on hemodialysis. Confirm the release form before prescribing.
GlobalRPh-hosted RX List · The RX List URL says mirapex, but its prescribing body is explicitly MIRAPEX ER. This record is ER only, not immediate-release.
Renal method: CrCl, mL/min. Source date: Revision date not established in selected retrieval. Retrieved: 2026-09-07
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Locally imported selected source sections; independent clinical review pending. Not a complete prescribing monograph.
Renal dosing, restrictions and evidence limits
For CrCl 30 to 50 mL/min, initiate the extended-release product every other day. After one week, careful assessment of tolerability and response may allow daily administration. Subsequent increments are 0.375 mg, no more often than weekly, up to 2.25 mg once daily. No reduction is recommended above 50 mL/min. This ER product is not recommended below 30 mL/min or in hemodialysis. Use the full ER label to select the starting strength; do not substitute an immediate-release renal table.
RDM33-rxlist-pramipexole-mirapex-er-C1 · Source locator: Dosage and administration: renal impairment; use in specific populations: renal impairment.
Source-specific limits
Product-identity warning: URL/heading is not sufficient to identify formulation.
GlobalRPh-hosted RX List · Pramipexole - MIRAPEX ER source-identity warning; selected renal passages, not a complete prescribing monograph.
Renal method: Creatinine clearance (CrCl), mL/min; equation not specified in the selected passage. Source date: Source revision date not established in selected retrieval. Retrieved: 2026-09-09
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.
Renal dosing, restrictions and evidence limits
SOURCE-IDENTITY WARNING: although the URL is mirapex, the retrieved prescribing body is MIRAPEX ER. Its CrCl 30-50 mL/min instructions start with every-other-day dosing, assess tolerance before daily dosing after 1 week, and permit further 0.375 mg increments no more often than weekly up to 2.25 mg/day. ER is not recommended below CrCl 30 or with hemodialysis because it was not studied. Do not use this page as an immediate-release or restless-legs dosing source. The separate official immediate-release record supplies its own renal table.
RDM50-rxlist-pramipexole-mirapex-er-d706416bd0-C1 · Source locator: ER formulation and renal dosage, lines 32-49 and 54-73; URL/title identity checked.
Source-specific limits
Not an IR source. URL wording is insufficient to establish product identity.
Renal method: Use the renal measure explicitly present in the RX passage. Source date: Mirror revision not established in the reviewed passage. Retrieved: 2026-11-07
Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.
Additional summaries stored on this page: 1 official-label, 3 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.
This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.
