GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Pitolisant (WAKIX)

Local RX List renal extractBase record retrieved 2026-09-07See the evidence for this drug1 sources available - open source summaries, references and comparisons

Wakix

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Renal guidance at a glance

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Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

Rxlist source

GlobalRPh RX List - Wakix

Product / population
Adult oral pitolisant only. Pediatric renal regimens are separate.
Renal measure
eGFR, mL/min/1.73 m2.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Adult renal dose subsection recovered through targeted search; pediatric table not imported.

Renal dosing, restrictions and evidence limits

For adult eGFR 15 to less than 60 mL/min/1.73 m2, start 8.9 mg once daily and increase after seven days to a maximum 17.8 mg once daily. Use below eGFR 15 is not recommended. Monitor patients with renal impairment for QTc prolongation. This adult regimen must not be transferred to pediatric patients, who have separate weight-based dose limits.

Source revision: Revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/wakix-drug/

Scope: Locally imported selected source sections; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

Full source card / provenance

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Source-first renal review

Evidence sources and renal implications

Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.

GlobalRPh RX List

GlobalRPh RX List - Wakix

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Adult oral pitolisant only. Pediatric renal regimens are separate.

Renal method: eGFR, mL/min/1.73 m2.
Retrieved: 2026-09-07

Read local renal resultOpen original reference

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

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Search the stored clinical text

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All source summaries, original wording and provenance
Before applying a renal protocol

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No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.

Share a reproducible source review

Choose sources below, then open a print-ready comparison with product scope, renal method, dates and cautions. Links can pin the exact local cards; they never contain patient values or choose a dose.

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Jump to renal guidanceClinician guide

Only one eligible source version is stored here. No second source is inferred from a reference link. Independent corroboration is still needed.

Build a source-review outline for documentation

This creates a blank decision outline with the source identities you select, not a dose recommendation or completed clinical assessment. No patient fields are collected, saved or sent. Complete the clinical decisions in your approved documentation system.

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Renal-context checklist: population, kidney trend and dialysis

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Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

Go directly to the relevant source section

Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

Compare or copy source versions

All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.

Original content / product scopeGlobalRPh RX List - Wakix
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://globalrph.com/rx-list/wakix-drug/

Product and population scope

Adult oral pitolisant only. Pediatric renal regimens are separate.

RDM33-SCOPE-pitolisant-wakix-C1 · Source section: Exact product identity and selected populationRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - Wakix

Open original reference

Open / share this exact local source

GlobalRPh-hosted RX List · Adult oral pitolisant only. Pediatric renal regimens are separate.

Renal method: eGFR, mL/min/1.73 m2.
Source date: Revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Locally imported selected source sections; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

For adult eGFR 15 to less than 60 mL/min/1.73 m2, start 8.9 mg once daily and increase after seven days to a maximum 17.8 mg once daily. Use below eGFR 15 is not recommended. Monitor patients with renal impairment for QTc prolongation. This adult regimen must not be transferred to pediatric patients, who have separate weight-based dose limits.

RDM33-rxlist-pitolisant-wakix-C1 · Source locator: Dosage recommendations: adults with renal impairment; renal impairment and QT warning.

Source-specific limits

Adult renal dose subsection recovered through targeted search; pediatric table not imported.

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/wakix-drug/
Retrieved
2026-09-07
Renal-function method
eGFR, mL/min/1.73 m2.
Source date/version
Revision date not established in selected retrieval.
Hash meaning
SHA-256 of the local authored summary only; original HTML/PDF/SPL bytes are not bundled or hashed.
Local summary SHA-256
e10a1461e636fb0ef9925e1c1a53d0908c3df20bf51e6e1e4e7bcdcecfdff69e

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/rx-list/wakix-drug/
Source retrieval
2026-09-07. This is not the source publication or label revision date.
Original source type
rxlist summary
Local text SHA-256
f5f5a1019d05f54c89273e24cbf15d38d6c4f538c43e5f3f0e508dc23a56e3c0
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

Read the full coverage report