GlobalRPh Renal Dosing Masterv6.6
GlobalRPh source record

Ofloxacin - systemic

Local RX List renal extractBase record retrieved 2026-09-05See the evidence for this drug2 sources available - open source summaries, references and comparisons
READ THE SOURCE-SPECIFIC ANSWER

Renal guidance at a glance

Cautions / source differences (1)

Confirm the product, indication and renal measure. The selected summary is not a complete prescribing monograph.

Choose a source to read (2)

Display order is not a clinical ranking. Date of retrieval is not the label revision date. Sources are never merged into one regimen. Other sources and conflicts remain below.

1 additional source qualifications - review before use
Introduction and table differ at exactly CrCl 50

The introductory adjustment trigger is <50, but the first table band includes 20-50. The dose unit remains indication-specific.

Before applying: Resolve exactly 50 against the applicable current product and institutional policy instead of silently assigning it.

Also check: Introduction and table differ at exactly CrCl 50

Rxlist source

GlobalRPh RX List - FLOXIN

Product / population
Systemic oral ofloxacin, not otic or ophthalmic products. Historical infection indications require current treatment-policy review.
Renal measure
Steady-state Cockcroft-Gault CrCl using actual body weight in the printed formula, mL/min.

RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.

Renal dosing, restrictions and evidence limits

After the usual initial dose, the renal table specifies: CrCl 20-50 mL/min, usual indication-specific unit dose every 24 hours; CrCl <20, one-half of that unit dose every 24 hours. The introductory text says adjustment below 50 but the table includes 50. Resolve that exact boundary before use; do not silently round into a band. A unit dose depends on indication.

Source revision: Source revision date not established in selected retrieval. | Retrieved: 2026-09-07. Retrieval date is not the revision date.

Source: https://globalrph.com/rx-list/floxin-drug/

Scope: Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph. GlobalRPh v6.6.

Full source card / provenance

All sources, comparison tools and evidence navigation
Source-first renal review

Evidence sources and renal implications

Choose a source to jump directly to its locally stored result. Qualitative precautions and evidence gaps remain visible even when no numerical clearance schedule is supplied.

Read 1 source difference / applicability notes

Preserved GlobalRPh source

Preserved original GlobalRPh source

Preserved historical content; not revalidated as current prescribing guidance.

Renal method: Read the measure and population stated in the original source sections.
Retrieved: 2026-09-05

Read local renal resultOpen original reference
GlobalRPh RX List

GlobalRPh RX List - FLOXIN

Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Systemic oral ofloxacin, not otic or ophthalmic products. Historical infection indications require current treatment-policy review.

Renal method: Steady-state Cockcroft-Gault CrCl using actual body weight in the printed formula, mL/min.
Retrieved: 2026-09-07

Read local renal resultOpen original reference

Source presence is not independent validation. A label mirror is not a second independent source; review the original reference and exact formulation.

Find text within this drug
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Search the stored clinical text

Locate a word or phrase within this drug's source summaries. Choose all sources or one source to focus the search. The selection never hides warnings or source text, changes a dose, or proves that a renal finding is absent.

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All source summaries, original wording and provenance
Before applying a renal protocol

Check the setting. Compare whole sources.

No patient-specific dose is calculated. Context choices only display reminders; they do not validate, hide or change any regimen.

Share a reproducible source review

Choose sources below, then open a print-ready comparison with product scope, renal method, dates and cautions. Links can pin the exact local cards; they never contain patient values or choose a dose.

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Jump to renal guidanceRead 1 difference / caution notesClinician guide

Select two distinct source versions. The complete stored summaries will appear below.

Build a source-review outline for documentation

This creates a blank decision outline with the source identities you select, not a dose recommendation or completed clinical assessment. No patient fields are collected, saved or sent. Complete the clinical decisions in your approved documentation system.

Choose one or two sources above or use the source checkboxes below.

Renal-context checklist: population, kidney trend and dialysis

These prompts are a reading aid, not a prescription checklist or proof that all requirements have been met. No selections are stored or sent to a server.

Read the exact source scope, renal metric and date before selecting a row. No applicability assessment has been performed.

See source-specific renal methods and the clinical interpretation guide for the supporting context.

Read before choosing a regimen

Source differences and product cautions

Search differences across all drugs

These are specific issues found during source review, not an automated judgment that one source is universally correct. A label mirror and its original label are not independent evidence.

threshold ambiguity

Introduction and table differ at exactly CrCl 50

The introductory adjustment trigger is <50, but the first table band includes 20-50. The dose unit remains indication-specific.

How to use this: Resolve exactly 50 against the applicable current product and institutional policy instead of silently assigning it.

GlobalRPh RX List - FLOXIN

Source-specific interpretation; independent clinician adjudication pending.

Go directly to the relevant source section

Renal dosing and precautions

Choose a source, then jump to its renal or dialysis section. These links locate stored text; they do not merge regimens or certify that sources agree.

New source summary - independent clinical review pending. Summaries of the identified label sections are included locally. Source import and numeric transcription checks are not independent two-reference validation. Do not treat this card as an approved institutional dosing protocol.

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

Compare or copy source versions

All content below is stored locally. Read a whole source version; do not combine its dose with another source's interval, renal metric or dialysis assumptions.

Original content / product scopeGlobalRPh RX List - FLOXIN
Choose two source checkboxes below.
Historical source content is not a current prescription. Original GlobalRPh recommendations are preserved, not automatically certified as current. Product-label and professional additions below are separately attributed. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.

Important source distinctions

Systemic dosing only; not an otic or ophthalmic product protocol.

Locally stored source content

Original GlobalRPh protocol

Clinical facts and comments transcribed into a structured reading format. This is not a byte-for-byte HTML archive. Original source: https://globalrph.com/renal/ofloxacin/

Usual Dosing (Adults)

200-400 mg orally or IV every 12 hours.

GRPH-ofloxacin-01 · Source section: Usual Dosing (Adults)Renal section finder

Renal Dosing

CrCl above 50 mL/min: no change. 20-50: 200-400 mg every 24 hours. Below 20: 100-200 mg every 24 hours (half the usual dose once daily).

GRPH-ofloxacin-02 · Source section: Renal DosingRenal section finder

Hemodialysis

The manufacturer discussion gives half the usual dose every 24 hours below CrCl 20 but no specific hemodialysis instructions. Continuous arteriovenous/venovenous hemodiafiltration: the separate source recommendation is 300 mg every 24 hours.

GRPH-ofloxacin-03 · Source section: HemodialysisRenal section finder
Locally imported selected renal sections

GlobalRPh RX List renal information

Rxlist

GlobalRPh RX List - FLOXIN

Open original reference

Open / share this exact local source

GlobalRPh-hosted RX List · Systemic oral ofloxacin, not otic or ophthalmic products. Historical infection indications require current treatment-policy review.

Renal method: Steady-state Cockcroft-Gault CrCl using actual body weight in the printed formula, mL/min.
Source date: Source revision date not established in selected retrieval.
Retrieved: 2026-09-07

Label mirror, not independent corroboration. This is selected locally stored RX List content. Full monograph import and current official-label review are not implied.
Dose or interval guidance. Use only the product, indication, renal metric and population described in this source.

Selected source text imported locally; independent clinical review pending. Not a complete prescribing monograph.

Renal dosing, restrictions and evidence limits

After the usual initial dose, the renal table specifies: CrCl 20-50 mL/min, usual indication-specific unit dose every 24 hours; CrCl <20, one-half of that unit dose every 24 hours. The introductory text says adjustment below 50 but the table includes 50. Resolve that exact boundary before use; do not silently round into a band. A unit dose depends on indication.

RDM41-rxlist-ofloxacin-25a2a9538f-C1 · Source locator: Dosage / Use in specific populations: renal impairment

Source identity and provenance
Source family
product_label_mirror
Source
https://globalrph.com/rx-list/floxin-drug/
Retrieved
2026-09-07
Renal-function method
Steady-state Cockcroft-Gault CrCl using actual body weight in the printed formula, mL/min.
Source date/version
Source revision date not established in selected retrieval.
Hash meaning
SHA-256 of local authored summary only; not original HTML, PDF or SPL bytes.
Local summary SHA-256
1aa205b1b4d4c61e8a61c14b4a1ceb44d3327204b89bd647f5d91f6d472169e4

Provenance and preservation

Additional summaries stored on this page: 0 official-label, 1 RX List, 0 professional, 0 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://globalrph.com/renal/ofloxacin/
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
globalrph individual
Local text SHA-256
c773fa88472bd263442dbd24e49319e3ba793c6e77556fb013c0a4d69c89e7cf
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

The original individual GlobalRPh pages commonly cite NIH/NLM DailyMed and instruct readers to review the applicable package insert for updates. That historical reference is preserved as context; it is not counted as an independently retrieved current label.

Read the full coverage report