GlobalRPh Renal Dosing Masterv6.6
Evidence addition

Micafungin (Mycamine)

Local official-label summaryBase record retrieved 2026-09-05See the evidence for this drug3 sources available - open source summaries, references and comparisons

Mycamine

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Official source

MYCAMINE - adult indication-specific dosing

Product / population
Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.
Renal measure
No renal-function dose bands specified for this summary.

Dosing / renal protocol and limits

Adult indicationIV dose once daily
Candidemia, disseminated Candida infection, Candida peritonitis or abscess100 mg
Esophageal candidiasis150 mg
Candida prophylaxis during hematopoietic stem-cell transplantation50 mg

Infuse over 1 hour. Renal impairment does not require adjustment, and no supplemental dose is required after hemodialysis. Monitor renal and hepatic tests despite the absence of a dose reduction. The label has not adequately studied Candida endocarditis, osteomyelitis or meningoencephalitis; the institutional high-dose protocols are separate recommendations.

Source revision: Selected label updated 2020-07-23; this older selected label is not a claim of latest manufacturer-wide revision. | Retrieved: 2026-09-05. Retrieval date is not the revision date.

Source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a064c4a7-25ec-4a2c-afc2-703491a4a38b

Scope: Locally included source-specific summary. Regimen differences are not automatically resolved. GlobalRPh v6.6.

Full source card / provenance

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Source-first renal review

Evidence sources and renal implications

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Official product label

MYCAMINE - adult indication-specific dosing

Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.

Renal method: No renal-function dose bands specified for this summary.
Retrieved: 2026-09-05

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Professional guidance

UCSF - micafungin by infection

Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.

Renal method: Qualitative no-adjustment recommendation.
Retrieved: 2026-09-05

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Handbook

Renal Drug Handbook, 5th edition - Micafungin

Historical adult renal/RRT summary. U.S. product identity anchored to the separate locally included DailyMed label. This is not a current U.S. product label.

Renal method: Book table headed GFR (mL/min); its preface states renal adjustments generally derive from Cockcroft-Gault CrCl. Do not silently relabel as indexed eGFR.
Retrieved: 2026-09-05

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Renal-context checklist: population, kidney trend and dialysis

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Renal dosing and precautions

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Handbook source

Renal Drug Handbook, 5th edition - Micafungin

Historical adult renal/RRT summary. U.S. product identity anchored to the separate locally included DailyMed label. This is not a current U.S. product label.

Method: Book table headed GFR (mL/min); its preface states renal adjustments generally derive from Cockcroft-Gault CrCl. Do not silently relabel as indexed eGFR.

Historical renal / replacement-therapy guidanceRead this complete source summary

No dialysis or renal heading shown? Read the complete source summary. Absence of a heading is not evidence that dose adjustment is unnecessary.

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Original content / product scopeMYCAMINE - adult indication-specific dosingUCSF - micafungin by infectionRenal Drug Handbook, 5th edition - Micafungin
Choose two source checkboxes below.
Exact product and population matter. This added page contains locally stored, source-specific clinical summaries. Historical handbook information, when present, is identified separately and may conflict with U.S. labeling. Confirm indication, population, kidney-function method, monitoring and the full prescribing information before applying a regimen.
Locally stored source content

Exact product and population

Product identity selected for the separately displayed source protocols below. Reference: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a064c4a7-25ec-4a2c-afc2-703491a4a38b

Product and population scope

Adult Micafungin (Mycamine). Use only the product, route, indication and renal-replacement setting explicitly stated in the source protocol selected below. Sources are alternatives to compare, not ingredients of a blended regimen.

SCOPE-micafungin · Source section: Editorial scope; each clinical recommendation is separately attributed belowRenal section finder
Separate U.S. product-label layer

FDA / DailyMed dosing and renal information

Official

MYCAMINE - adult indication-specific dosing

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NIH/NLM DailyMed - U.S. product labeling · Adults; named product and route only. Selected dosing and renal summary, not the full prescribing information.

Renal method: No renal-function dose bands specified for this summary.
Source date: Selected label updated 2020-07-23; this older selected label is not a claim of latest manufacturer-wide revision.
Retrieved: 2026-09-05

Locally included source-specific summary. Regimen differences are not automatically resolved.

Dosing / renal protocol and limits

Adult indicationIV dose once daily
Candidemia, disseminated Candida infection, Candida peritonitis or abscess100 mg
Esophageal candidiasis150 mg
Candida prophylaxis during hematopoietic stem-cell transplantation50 mg

Infuse over 1 hour. Renal impairment does not require adjustment, and no supplemental dose is required after hemodialysis. Monitor renal and hepatic tests despite the absence of a dose reduction. The label has not adequately studied Candida endocarditis, osteomyelitis or meningoencephalitis; the institutional high-dose protocols are separate recommendations.

RDM30-076-micafungin-1 · Source locator: MYCAMINE - adult indication-specific dosing; renal/dosing sections and stated qualifiers

Source identity and provenance
Source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a064c4a7-25ec-4a2c-afc2-703491a4a38b
Retrieved
2026-09-05
DailyMed Set ID
a064c4a7-25ec-4a2c-afc2-703491a4a38b
Renal-function method
No renal-function dose bands specified for this summary.
Source date/version
Selected label updated 2020-07-23; this older selected label is not a claim of latest manufacturer-wide revision.
Hash meaning
Locally authored summary text; not original SPL, HTML or PDF bytes
Local summary SHA-256
9771c73bff75fa6c14ebf740650f9aff32dc7420fa800c6a13c2089b4d154344
Separate handbook layer

Renal Drug Handbook cross-check

Handbook

Renal Drug Handbook, 5th edition - Micafungin

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UK Renal Pharmacy Group / CRC Press · Historical adult renal/RRT summary. U.S. product identity anchored to the separate locally included DailyMed label. This is not a current U.S. product label.

Renal method: Book table headed GFR (mL/min); its preface states renal adjustments generally derive from Cockcroft-Gault CrCl. Do not silently relabel as indexed eGFR.
Source date: 5th edition; 2019 copyright; historical reference
Retrieved: 2026-09-05

Historical handbook cross-check; not a current U.S. protocol

Historical renal / replacement-therapy guidance

The 20-50, 10-20 and <10 mL/min bands retain the usual indication-specific dose. PD, HD, high-flux and continuous therapy also retain usual doses; the book describes no dialysis removal. Its broad dose range is indication- and weight-dependent, so use the separate U.S. adult indication doses. The book notes reports of renal dysfunction/AKI despite the no-adjustment recommendation.

HB30-micafungin-1 · Source locator: Printed page 655: renal impairment, RRT and other information

Source-specific limits

Separate source recommendation, not proof of agreement or contemporary clinical validation. Dialysis predictions are retained with their original certainty.

Source identity and provenance
Retrieved
2026-09-05
Handbook page
5th edition, printed p. 655; uploaded PDF p. 674
Renal-function method
Book table headed GFR (mL/min); its preface states renal adjustments generally derive from Cockcroft-Gault CrCl. Do not silently relabel as indexed eGFR.
Source date/version
5th edition; 2019 copyright; historical reference
U.S. product identity basis
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a064c4a7-25ec-4a2c-afc2-703491a4a38b
Hash meaning
Local paraphrase; original book not redistributed
Local summary SHA-256
c8e813f2ec9efa47c74c6d5dfa63e9a818c720c5478c1e99e1fa0184e8da8ddb
Separate professional-source layer

University and professional protocols

Professional

UCSF - micafungin by infection

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UCSF Infectious Diseases Management Program · Adults; source-specific institutional guidance. Match route, indication and renal replacement modality.

Renal method: Qualitative no-adjustment recommendation.
Source date: Revision date not stated in the reviewed page.
Retrieved: 2026-09-05

Locally included source-specific summary. Regimen differences are not automatically resolved.

Dosing / renal protocol and limits

For candidemia, invasive candidiasis and the listed ICU/neutropenic empiric-treatment settings, the adult regimen is 100 mg IV daily. Esophageal candidiasis, endocarditis and cardiac-device infection use 150 mg daily. Candida prevention in selected transplant, neutropenic or hematologic-malignancy patients uses 50-100 mg daily.

UCSF retains these doses in renal dysfunction and its dialysis table. Obesity, elevated MICs and some deep infections may require specialist-directed higher doses. This institutional indication list is broader than some labeled uses.

RDM30-035-micafungin-1 · Source locator: UCSF - micafungin by infection; renal/dosing sections and stated qualifiers

Source identity and provenance
Source
https://idmp.ucsf.edu/content/micafungin
Retrieved
2026-09-05
Renal-function method
Qualitative no-adjustment recommendation.
Source date/version
Revision date not stated in the reviewed page.
Hash meaning
Locally authored summary text; not original SPL, HTML or PDF bytes
Local summary SHA-256
b2e51aa16001c4ccae896476df17b08db7555d45f385ffe17e0c20a0df772f83

Provenance and preservation

Additional summaries stored on this page: 1 official-label, 0 RX List, 1 professional, 1 handbook. Empty additional-source groups are not shown. A missing layer is not a no-adjustment recommendation.

Original source
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a064c4a7-25ec-4a2c-afc2-703491a4a38b
Source retrieval
2026-09-05. This is not the source publication or label revision date.
Original source type
multisource addition
Local text SHA-256
6c6464fa31c4d57c684265bebb54762af8f8567a085de78442858b02df03d00e
Import versus clinical validation
Source-section locators identify where retained content came from. A source-section identifier does not assert that every numeric statement has been independently corroborated. The local text hash is not a hash of original HTML, an FDA PDF or SPL XML.

This page is an additional exact-product entry, not a recovered GlobalRPh monograph. Its primary scope text and separately attributed clinical summaries are locally included.

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