GlobalRPh RX List - ENGERIX-B dialysis
- Product / population
- IM ENGERIX-B adult vaccine, 20 mcg/mL, dialysis-specific schedule
- Renal measure
- Adult hemodialysis population; anti-HBs monitoring
RX mirror: this is not independent corroboration of its underlying label. Check dated-label and formulation limitations.
Renal dosing, restrictions and evidence limits
For adults on hemodialysis, the source specifies 40 mcg (2 mL) IM at months 0, 1, 2 and 6. Each visit may use one 2-mL dose or two 1-mL doses of the 20-mcg/mL adult formulation. This four-dose schedule differs from the RECOMBIVAX HB dialysis schedule.
Antibody responses may be lower and less durable in hemodialysis. Check antibody levels annually; give a 2-mL booster if anti-HBs falls below 10 mIU/mL. Do not confuse routine adult dosing or a general alternate schedule with the dialysis-specific instructions.